HitPredict

Interactor 1: H2AZ (P0C0S5)
Histone H2A.Z (H2A/z)
Gene: H2AZ1

Interactor 2: H32 (Q71DI3)
Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (Histone H3/m) (Histone H3/o)
Gene: H3C15

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	28242625, 34349018, 37071682
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~Histone, Histone~Histone_H2A_C
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0006325 - chromatin organization GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 128 Hs			1 136
+	Hs
		469993 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Mm
		470229 H2AZ_MOUSE (1-128): 9.79e-62: 186: 100.00		H31_MOUSE (1-136): 1.98e-62: 189: 99.27
+	Hs
		470036 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Mm
		470230 H2AZ_MOUSE (1-128): 9.79e-62: 186: 100.00		H32_MOUSE (1-136): 3.73e-61: 186: 100.00
+	Mm
		470231 H2AZ_MOUSE (1-128): 9.79e-62: 186: 100.00		H33_MOUSE (1-136): 1.59e-61: 186: 97.06
+	Hs
		934914 H2AV_HUMAN (1-127): 2.06e-60: 183: 98.43		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		1086191 H2AV_HUMAN (1-127): 2.06e-60: 183: 98.43		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		1157204 H2AV_HUMAN (1-127): 2.06e-60: 183: 98.43		H3C_HUMAN (1-136): 8.83e-59: 179: 94.12
+	Hs
		935141 H2A1A_HUMAN (5-125): 2.16e-56: 173: 61.48		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		934946 H2A2B_HUMAN (5-127): 9.2e-56: 171: 59.68		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		935170 H2A1J_HUMAN (5-125): 1.24e-55: 171: 61.48		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Mm
		935458 Q8CGP4_MOUSE (5-127): 1.37e-55: 171: 59.68		H31_MOUSE (1-136): 1.98e-62: 189: 99.27
+	Hs
		1086203 H2A2B_HUMAN (5-127): 9.2e-56: 171: 59.68		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		1086293 H2A1J_HUMAN (5-125): 1.24e-55: 171: 61.48		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		1174640 H2A1J_HUMAN (5-125): 1.24e-55: 171: 61.48		H32_HUMAN (1-136): 3.73e-61: 186: 100.00
+	Mm
		952264 Q8CGP4_MOUSE (5-127): 1.37e-55: 171: 59.68		H32_MOUSE (1-136): 3.73e-61: 186: 100.00
+	Hs
		952450 H2A2B_HUMAN (5-127): 9.2e-56: 171: 59.68		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Mm
		952759 Q8CGP4_MOUSE (5-127): 1.37e-55: 171: 59.68		H33_MOUSE (1-136): 1.59e-61: 186: 97.06
+	Hs
		1157222 H2A1J_HUMAN (5-125): 1.24e-55: 171: 61.48		H3C_HUMAN (1-136): 8.83e-59: 179: 94.12
+	Hs
		469965 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00