HitPredict

Interactor 1: H2AZ (P0C0S5)
Histone H2A.Z (H2A/z)
Gene: H2AZ1

Interactor 2: PB1 (Q86U86)
Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D)
Gene: PBRM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	28242625, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	BAH~Histone
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 128 Hs			1 1689
+	Hs
		1087035 H2A2C_HUMAN (5-127): 3.47e-55: 170: 61.29		PB1_HUMAN (1-1689): 0: 1223: 100.00
+	Hs
		391768 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		PB1_HUMAN (1-1689): 0: 1223: 100.00
+	Xl
		936145 H2AZL_XENLA (1-128): 2.23e-60: 183: 89.84		P79922_XENLA (585-1361): 7.33e-72: 268: 13.31
+	Hs
		641230 H2A2C_HUMAN (5-127): 3.47e-55: 170: 61.29		DNMT1_HUMAN (301-1361): 1.76e-75: 280: 12.20
+	Xl
		420791 H2A1_XENLA (5-127): 5.37e-55: 169: 58.07		P79922_XENLA (585-1361): 7.33e-72: 268: 13.31
+	Hs
		470106 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		PHIP_HUMAN (480-1024): 4.44e-53: 207: 13.50
+	Hs
		1087066 H2A2C_HUMAN (5-127): 3.47e-55: 170: 61.29		PHIP_HUMAN (480-1024): 4.44e-53: 207: 13.50
+	Hs
		1067021 H2AV_HUMAN (1-127): 2.06e-60: 183: 98.43		BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76
+	Hs
		1067038 H2A2B_HUMAN (5-127): 9.2e-56: 171: 59.68		BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76
+	Hs
		1066979 H2A2C_HUMAN (5-127): 3.47e-55: 170: 61.29		BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76
+	Hs
		555470 H2AX_HUMAN (5-124): 1.08e-54: 169: 61.98		BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76
+	Hs
		469949 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		BRD2_HUMAN (2-169): 7.14e-20: 98.6: 15.29
+	Hs
		470151 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		BRD8_HUMAN (301-506): 2.43e-17: 90.8: 14.55
+	Hs
		631492 H2A2B_HUMAN (5-127): 9.2e-56: 171: 59.68		BRD2_HUMAN (2-169): 7.14e-20: 98.6: 15.29
+	Hs
		391554 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		BRD2_HUMAN (2-169): 7.14e-20: 98.6: 15.29
+	Hs
		555299 H2AX_HUMAN (5-124): 1.08e-54: 169: 61.98		BRD2_HUMAN (2-169): 7.14e-20: 98.6: 15.29
+	Mm
		470232 H2AZ_MOUSE (1-128): 9.79e-62: 186: 100.00		SMCA4_MOUSE (748-881): 2.04e-12: 74.9: 23.19
+	Hs
		469971 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		SMCA4_HUMAN (764-881): 7.55e-11: 69.5: 23.58
+	Hs
		555359 H2AX_HUMAN (5-124): 1.08e-54: 169: 61.98		SMCA4_HUMAN (764-881): 7.55e-11: 69.5: 23.58
+	Hs
		555358 H2AX_HUMAN (5-124): 1.08e-54: 169: 61.98		SMCA2_HUMAN (794-881): 2.15e-09: 64.9: 26.09