HitPredict

Interactor 1: H2AZ (P0C0S5)
Histone H2A.Z (H2A/z)
Gene: H2AZ1

Interactor 2: SP16H (Q9Y5B9)
FACT complex subunit SPT16 (Chromatin-specific transcription elongation factor 140 kDa subunit) (FACT 140 kDa subunit) (FACTp140) (Facilitates chromatin transcription complex subunit SPT16) (hSPT16)
Gene: SUPT16H

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	33961781, 24463511
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~Rtt106, Histone_H2A_C~Rtt106
Common GO terms	GO:0005634 - nucleus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 128 Hs			1 1047
+	Hs
		1312248 H2AJ_HUMAN (5-127): 8.35e-56: 171: 60.48		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		1087145 H2A2C_HUMAN (5-127): 3.47e-55: 170: 61.29		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Mm
		650195 H2AX_MOUSE (5-124): 1.8e-54: 169: 61.98		SP16H_MOUSE (1-1047): 0: 1332: 98.66
+	Hs
		1151400 H2A2A_HUMAN (5-125): 4.61e-55: 169: 62.30		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		1185216 H2A3_HUMAN (5-125): 5.08e-55: 169: 62.30		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		391984 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		470626 H2A1_HUMAN (5-125): 8.23e-55: 169: 61.48		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		555708 H2AX_HUMAN (5-124): 1.08e-54: 169: 61.98		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Sc
		692987 H2AZ_YEAST (4-126): 3.32e-39: 129: 65.91		SPT16_YEAST (3-1008): 0: 938: 33.49