HitPredict

Interactor 1: H2AZ (P0C0S6)
Histone H2A.Z (H2A/z)
Gene: H2az1

Interactor 2: SMCA4 (Q3TKT4)
Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4)
Gene: Smarca4

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	23260146
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0000791 - euchromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 128 Mm			1 1613
+	Hs
		469971 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		SMCA4_HUMAN (1-1613): 0: 1071: 97.21
+	Hs
		229286 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		SMCA5_HUMAN (596-1579): 0: 795: 27.82
+	Hs
		469951 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		SMCA1_HUMAN (636-1579): 0: 781: 29.46
+	Hs
		229433 H2A2B_HUMAN (5-127): 9.2e-56: 171: 59.68		SMCA5_HUMAN (596-1579): 0: 795: 27.82
+	Hs
		229279 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		SMCA5_HUMAN (596-1579): 0: 795: 27.82
+	Hs
		229296 H2AX_HUMAN (5-124): 1.08e-54: 169: 61.98		SMCA5_HUMAN (596-1579): 0: 795: 27.82
+	Hs
		555306 H2AX_HUMAN (5-124): 1.08e-54: 169: 61.98		SMCA1_HUMAN (636-1579): 0: 781: 29.46
+	Hs
		470021 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		CHD4_HUMAN (413-1587): 0: 713: 21.88
+	Hs
		470170 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		CHD8_HUMAN (13-1454): 0: 712: 21.06
+	Hs
		1018640 H2A1H_HUMAN (5-125): 2.98e-55: 170: 61.48		CHD3_HUMAN (425-1613): 0: 719: 22.49
+	Hs
		391675 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		CHD3_HUMAN (425-1613): 0: 719: 22.49
+	Hs
		1059717 H2A2B_HUMAN (5-127): 9.2e-56: 171: 59.68		CHD4_HUMAN (413-1587): 0: 713: 21.88
+	Hs
		1059647 H2A2C_HUMAN (5-127): 3.47e-55: 170: 61.29		CHD4_HUMAN (413-1587): 0: 713: 21.88
+	Hs
		1059795 H2A1H_HUMAN (5-125): 2.98e-55: 170: 61.48		CHD4_HUMAN (413-1587): 0: 713: 21.88
+	Hs
		391704 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		CHD4_HUMAN (413-1587): 0: 713: 21.88
+	Hs
		391915 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		CHD8_HUMAN (13-1454): 0: 712: 21.06
+	Hs
		470077 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		CHD1L_HUMAN (741-1474): 0: 693: 33.59
+	Hs
		391728 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		CHD9_HUMAN (46-1384): 0: 702: 21.95
+	Hs
		1185203 H2A3_HUMAN (5-125): 5.08e-55: 169: 62.30		CHD1L_HUMAN (741-1474): 0: 693: 33.59
+	Hs
		151474 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		CHD2_HUMAN (343-1439): 0: 667: 27.19