HitPredict

Interactor 1: H2A1 (P0C0S8)
Histone H2A type 1 (H2A.1) (Histone H2A/ptl)
Gene: H2AC11

Interactor 2: CBX1 (P83916)
Chromobox protein homolog 1 (HP1Hsbeta) (Heterochromatin protein 1 homolog beta) (HP1 beta) (Heterochromatin protein p25) (M31) (Modifier 1 protein) (p25beta)
Gene: CBX1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0019899 - enzyme binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 130 Hs			1 185
+	Hs
		594841 H2A1D_HUMAN (1-130): 9.47e-68: 202: 99.23		CBX3_HUMAN (1-177): 2.11e-63: 195: 69.49
+	Hs
		594840 H2A1D_HUMAN (1-130): 9.47e-68: 202: 99.23		CBX1_HUMAN (1-185): 2.21e-62: 193: 100.00
+	Hs
		391654 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		CBX1_HUMAN (1-185): 2.21e-62: 193: 100.00
+	Hs
		800438 H2A3_HUMAN (1-130): 9.27e-68: 202: 97.69		CBX5_HUMAN (1-183): 9.59e-60: 186: 57.45
+	Hs
		555444 H2AX_HUMAN (1-129): 8.34e-64: 192: 91.47		CBX3_HUMAN (1-177): 2.11e-63: 195: 69.49
+	Hs
		555335 H2AX_HUMAN (1-129): 8.34e-64: 192: 91.47		CBX5_HUMAN (1-183): 9.59e-60: 186: 57.45
+	Hs
		203730 H2A2B_HUMAN (1-130): 2.11e-66: 198: 94.62		SUV91_HUMAN (13-121): 4.22e-29: 112: 21.10
+	Hs
		203696 H2A2C_HUMAN (1-130): 3.65e-65: 195: 96.92		SUV91_HUMAN (13-121): 4.22e-29: 112: 21.10
+	Hs
		470614 H2A1_HUMAN (1-130): 8.4e-68: 202: 100.00		CDYL_HUMAN (7-120): 2.53e-25: 103: 25.86
+	Hs
		315950 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		CBX6_HUMAN (12-101): 1.25e-25: 103: 30.00
+	Hs
		391702 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		CBX2_HUMAN (10-110): 2.55e-25: 103: 29.70
+	Hs
		391975 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		CDYL_HUMAN (7-120): 2.53e-25: 103: 25.86
+	Hs
		123160 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		CBX4_HUMAN (12-89): 1e-24: 101: 34.62
+	Hs
		316082 H2A2B_HUMAN (1-130): 2.11e-66: 198: 94.62		CBX6_HUMAN (12-101): 1.25e-25: 103: 30.00
+	Hs
		391912 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		CBX8_HUMAN (12-88): 1.45e-24: 100: 35.07
+	Hs
		391989 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		CDY2_HUMAN (18-110): 2.53e-23: 97.9: 25.00
+	Hs
		1087137 H2A2C_HUMAN (1-130): 3.65e-65: 195: 96.92		CDYL_HUMAN (7-120): 2.53e-25: 103: 25.86
+	Hs
		1312232 H2AJ_HUMAN (1-126): 5.48e-65: 195: 96.03		CBX8_HUMAN (12-88): 1.45e-24: 100: 35.07
+	Hs
		555696 H2AX_HUMAN (1-129): 8.34e-64: 192: 91.47		CDYL_HUMAN (7-120): 2.53e-25: 103: 25.86
+	Dm
		639959 H2A_DROME (17-125): 8.06e-60: 181: 89.91		PC_DROME (2-80): 1.9e-14: 72.2: 35.44