HitPredict

Interactor 1: H2A1 (P0C0S8)
Histone H2A type 1 (H2A.1) (Histone H2A/ptl)
Gene: H2AC11

Interactor 2: NP1L4 (Q99733)
Nucleosome assembly protein 1-like 4 (Nucleosome assembly protein 2) (NAP-2)
Gene: NAP1L4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	33961781, 24463511
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~NAP
Common GO terms	GO:0005634 - nucleus
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 130 Hs			1 375
+	Hs
		391863 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		NP1L4_HUMAN (1-375): 2.5e-142: 410: 100.00
+	Hs
		1087091 H2A2C_HUMAN (1-130): 3.65e-65: 195: 96.92		NP1L4_HUMAN (1-375): 2.5e-142: 410: 100.00
+	Hs
		470307 H2A1_HUMAN (1-130): 8.4e-68: 202: 100.00		NP1L1_HUMAN (21-336): 1.38e-123: 363: 67.72
+	Hs
		391616 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		NP1L1_HUMAN (21-336): 1.38e-123: 363: 67.72
+	Hs
		876839 H2A2B_HUMAN (1-130): 2.11e-66: 198: 94.62		NP1L1_HUMAN (21-336): 1.38e-123: 363: 67.72
+	Hs
		876804 H2A2C_HUMAN (1-130): 3.65e-65: 195: 96.92		NP1L1_HUMAN (21-336): 1.38e-123: 363: 67.72
+	Hs
		555373 H2AX_HUMAN (1-129): 8.34e-64: 192: 91.47		NP1L1_HUMAN (21-336): 1.38e-123: 363: 67.72
+	Dm
		950430 H2A_DROME (17-125): 8.06e-60: 181: 89.91		Q24150_DROME (55-340): 2.54e-109: 326: 51.05
+	Dm
		950446 H2A_DROME (17-125): 8.06e-60: 181: 89.91		Q9W1G7_DROME (55-340): 2.04e-109: 326: 51.05
+	Sc
		392309 H2A2_YEAST (16-128): 2.5e-59: 180: 80.53		NAP1_YEAST (14-338): 4.8e-95: 291: 33.94
+	Sc
		392059 H2A1_YEAST (16-127): 4.04e-53: 165: 81.25		NAP1_YEAST (14-338): 4.8e-95: 291: 33.94
+	Ce
		452190 H2A_CAEEL (17-121): 2.31e-54: 168: 90.48		Q19007_CAEEL (40-363): 3.1e-91: 278: 36.70
+	Hs
		391771 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		TSYL5_HUMAN (112-368): 1.78e-63: 210: 15.00
+	Hs
		391896 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		TSYL1_HUMAN (113-336): 1.52e-63: 210: 17.86
+	Hs
		555417 H2AX_HUMAN (1-129): 8.34e-64: 192: 91.47		SET_HUMAN (92-336): 2.56e-62: 203: 20.82