HitPredict

Interactor 1: H2A1 (P0C0S8)
Histone H2A type 1 (H2A.1) (Histone H2A/ptl)
Gene: H2AC11

Interactor 2: PCGF1 (Q9BSM1)
Polycomb group RING finger protein 1 (Nervous system Polycomb-1) (NSPc1) (RING finger protein 68)
Gene: PCGF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26687479
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~zf-C3HC4_2
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 130 Hs			1 259
+	Hs
		391879 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		PCGF1_HUMAN (1-259): 4.13e-82: 248: 100.00
+	Hs
		470285 H2A1_HUMAN (1-130): 8.4e-68: 202: 100.00		BMI1_HUMAN (30-255): 1.92e-63: 203: 35.29
+	Hs
		717932 H2A2A_HUMAN (1-130): 6.74e-68: 202: 98.46		BMI1_HUMAN (30-255): 1.92e-63: 203: 35.29
+	Hs
		391572 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		BMI1_HUMAN (30-255): 1.92e-63: 203: 35.29
+	Hs
		717876 H2A2C_HUMAN (1-130): 3.65e-65: 195: 96.92		BMI1_HUMAN (30-255): 1.92e-63: 203: 35.29
+	Hs
		555322 H2AX_HUMAN (1-129): 8.34e-64: 192: 91.47		BMI1_HUMAN (30-255): 1.92e-63: 203: 35.29
+	Hs
		1151374 H2A2A_HUMAN (1-130): 6.74e-68: 202: 98.46		RING2_HUMAN (24-259): 7.12e-39: 140: 16.88
+	Hs
		1185208 H2A3_HUMAN (1-130): 9.27e-68: 202: 97.69		RING2_HUMAN (24-259): 7.12e-39: 140: 16.88
+	Hs
		470514 H2A1_HUMAN (1-130): 8.4e-68: 202: 100.00		RING2_HUMAN (24-259): 7.12e-39: 140: 16.88
+	Hs
		391856 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		RING2_HUMAN (24-259): 7.12e-39: 140: 16.88
+	Hs
		1216249 H2A2B_HUMAN (1-130): 2.11e-66: 198: 94.62		RING2_HUMAN (24-259): 7.12e-39: 140: 16.88
+	Hs
		1087089 H2A2C_HUMAN (1-130): 3.65e-65: 195: 96.92		RING2_HUMAN (24-259): 7.12e-39: 140: 16.88
+	Hs
		555611 H2AX_HUMAN (1-129): 8.34e-64: 192: 91.47		RING2_HUMAN (24-259): 7.12e-39: 140: 16.88
+	Hs
		1307111 H2A1J_HUMAN (1-128): 2.78e-67: 201: 99.22		TRI31_HUMAN (32-246): 2.35e-32: 124: 17.27
+	Hs
		391666 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		RING1_HUMAN (24-155): 3.14e-32: 123: 20.59
+	Mm
		1145461 H2A2C_MOUSE (1-130): 3.65e-65: 195: 96.92		CHFR_MOUSE (8-187): 3.69e-31: 123: 17.30
+	Hs
		555425 H2AX_HUMAN (1-129): 8.34e-64: 192: 91.47		RING1_HUMAN (24-155): 3.14e-32: 123: 20.59
+	Hs
		282470 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		RNF8_HUMAN (24-130): 3e-10: 61.7: 28.04
+	Hs
		282668 H2A2C_HUMAN (1-130): 3.65e-65: 195: 96.92		RNF8_HUMAN (24-130): 3e-10: 61.7: 28.04
+	Hs
		282515 H2AX_HUMAN (1-129): 8.34e-64: 192: 91.47		RNF8_HUMAN (24-130): 3e-10: 61.7: 28.04