Interactor 1: DEGP (P0C0V0)
Periplasmic serine endoprotease DegP (EC 3.4.21.107) (Heat shock protein DegP) (Protease Do)
Gene: DEGP

Interactor 2: DEGP (P0C0V0)
Periplasmic serine endoprotease DegP (EC 3.4.21.107) (Heat shock protein DegP) (Protease Do)
Gene: DEGP

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.974

The method score is based on:

Property Details
Experiments 18496527, 18697939, 20581825, 20581826, 21893291, 24373769, 21458668
Identification Methods x-ray crystallography, molecular sieving, 3D electron microscopy, dynamic light scattering, cross-linking study, cosedimentation in solution, mass spectrometry studies of complexes, protease assay
Interaction Type direct interaction, protein cleavage, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PDZ~PDZ, PDZ~Trypsin_2, Trypsin_2~Trypsin_2
Common GO terms GO:0004252 - serine-type endopeptidase activity
GO:0005886 - plasma membrane
GO:0006457 - protein folding
GO:0006508 - proteolysis
GO:0006515 - protein quality control for misfolded or incompletely synthesized proteins
and 10 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 474
Ec

1 474
+ Ec
+ At
+ Ss
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ec
+ Hs
+ At
+ Sp
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024