HitPredict

Interactor 1: H2AB1 (P0C5Y9)
Histone H2A-Bbd type 1 (H2A Barr body-deficient) (H2A.B) (H2A.Bbd)
Gene: H2AB1

Interactor 2: PELP1 (Q8IZL8)
Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of non-genomic activity of estrogen receptor) (Transcription factor HMX3)
Gene: PELP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000791 - euchromatin GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 115 Hs			1 1130
+	Hs
		472888 H2AB2_HUMAN (1-115): 5.32e-65: 194: 99.13		PELP1_HUMAN (1-1130): 0: 788: 100.00
+	Hs
		555540 H2AX_HUMAN (7-109): 6.03e-51: 159: 47.57		PELP1_HUMAN (1-1130): 0: 788: 100.00
+	Hs
		1087047 H2A2C_HUMAN (7-109): 3.16e-50: 157: 45.63		PELP1_HUMAN (1-1130): 0: 788: 100.00
+	Hs
		470454 H2A1_HUMAN (7-109): 4.1e-50: 156: 45.63		PELP1_HUMAN (1-1130): 0: 788: 100.00
+	Hs
		391789 H2A1B_HUMAN (7-109): 7.99e-50: 155: 44.66		PELP1_HUMAN (1-1130): 0: 788: 100.00
+	Hs
		554260 H2AX_HUMAN (7-109): 6.03e-51: 159: 47.57		MUC1_HUMAN (443-1092): 6.43e-28: 124: 11.79
+	Hs
		391823 H2A1B_HUMAN (7-109): 7.99e-50: 155: 44.66		CBP_HUMAN (631-1010): 2.14e-28: 126: 16.87
+	Hs
		472802 H2AB1_HUMAN (1-115): 3e-66: 197: 100.00		MDC1_HUMAN (411-1014): 5.18e-12: 72.8: 11.24
+	Hs
		1273164 H2A1H_HUMAN (7-109): 2.18e-50: 157: 45.63		PRG4_HUMAN (464-1117): 2.09e-18: 93.6: 12.61
+	Mm
		101453 H2A3_MOUSE (7-109): 4.1e-50: 156: 45.63		F8VPR5_MOUSE (679-1121): 6.98e-14: 78.9: 11.49
+	Hs
		555463 H2AX_HUMAN (7-109): 6.03e-51: 159: 47.57		MDC1_HUMAN (411-1014): 5.18e-12: 72.8: 11.24
+	Hs
		998866 H2A2B_HUMAN (7-109): 2.22e-51: 160: 47.57		EP300_HUMAN (697-1081): 1.18e-11: 71.5: 11.17
+	Hs
		555430 H2AX_HUMAN (7-109): 6.03e-51: 159: 47.57		EP300_HUMAN (697-1081): 1.18e-11: 71.5: 11.17
+	Hs
		998781 H2A2C_HUMAN (7-109): 3.16e-50: 157: 45.63		EP300_HUMAN (697-1081): 1.18e-11: 71.5: 11.17
+	Hs
		391610 H2A1B_HUMAN (7-109): 7.99e-50: 155: 44.66		SC24C_HUMAN (724-1113): 9.5e-12: 71.6: 9.31
+	Hs
		391671 H2A1B_HUMAN (7-109): 7.99e-50: 155: 44.66		EP300_HUMAN (697-1081): 1.18e-11: 71.5: 11.17
+	Hs
		391802 H2A1B_HUMAN (7-109): 7.99e-50: 155: 44.66		KMT2C_HUMAN (704-1130): 8.21e-11: 68.9: 9.28