HitPredict

Interactor 1: H2AB2 (P0C5Z0)
Histone H2A-Bbd type 2/3 (H2A Barr body-deficient) (H2A.Bbd)
Gene: H2AB2

Interactor 2: H2B1L (Q99880)
Histone H2B type 1-L (Histone H2B.c) (H2B/c)
Gene: H2BC13

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0006334 - nucleosome assembly GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 115 Hs			1 126
+	Hs
		472972 H2AB2_HUMAN (1-115): 8.9e-66: 196: 100.00		U3KQK0_HUMAN (1-126): 1.67e-55: 172: 97.62
+	Hs
		241426 H2AB2_HUMAN (1-115): 8.9e-66: 196: 100.00		H2B1K_HUMAN (1-126): 4.5e-54: 167: 97.62
+	Hs
		420795 H2AB2_HUMAN (1-115): 8.9e-66: 196: 100.00		H2B1J_HUMAN (1-126): 2.66e-54: 167: 96.83
+	Hs
		472923 H2AB2_HUMAN (1-115): 8.9e-66: 196: 100.00		H2B1N_HUMAN (1-126): 1.29e-53: 166: 97.62
+	Hs
		1087239 H2A2B_HUMAN (7-109): 2.22e-51: 160: 48.54		H2B2E_HUMAN (1-126): 2.16e-54: 168: 97.62
+	Hs
		1216239 H2A2B_HUMAN (7-109): 2.22e-51: 160: 48.54		H2B1H_HUMAN (1-126): 2.44e-54: 168: 97.62
+	Hs
		555295 H2AX_HUMAN (7-109): 6.03e-51: 159: 48.54		H2B1O_HUMAN (1-126): 1.18e-54: 168: 96.83
+	Hs
		555487 H2AX_HUMAN (7-109): 6.03e-51: 159: 48.54		H2B2E_HUMAN (1-126): 2.16e-54: 168: 97.62
+	Hs
		555496 H2AX_HUMAN (7-109): 6.03e-51: 159: 48.54		H2B2F_HUMAN (1-126): 9.5e-55: 168: 96.83
+	Hs
		918497 H2A2B_HUMAN (7-109): 2.22e-51: 160: 48.54		H2B1C_HUMAN (1-126): 4.4e-54: 167: 98.41
+	Hs
		241436 H2AX_HUMAN (7-109): 6.03e-51: 159: 48.54		H2B1K_HUMAN (1-126): 4.5e-54: 167: 97.62
+	Hs
		420800 H2AX_HUMAN (7-109): 6.03e-51: 159: 48.54		H2B1J_HUMAN (1-126): 2.66e-54: 167: 96.83
+	Hs
		555376 H2AX_HUMAN (7-109): 6.03e-51: 159: 48.54		H2BFS_HUMAN (1-126): 4.22e-54: 167: 96.03
+	Hs
		555396 H2AX_HUMAN (7-109): 6.03e-51: 159: 48.54		H2B1C_HUMAN (1-126): 4.4e-54: 167: 98.41
+	Hs
		707681 H2A2B_HUMAN (7-109): 2.22e-51: 160: 48.54		H2B1B_HUMAN (1-126): 5.99e-54: 166: 96.03
+	Hs
		886151 H2A2B_HUMAN (7-109): 2.22e-51: 160: 48.54		H2B1D_HUMAN (1-126): 1.27e-53: 166: 97.62
+	Hs
		555317 H2AX_HUMAN (7-109): 6.03e-51: 159: 48.54		H2B1B_HUMAN (1-126): 5.99e-54: 166: 96.03
+	Hs
		555377 H2AX_HUMAN (7-109): 6.03e-51: 159: 48.54		H2B1D_HUMAN (1-126): 1.27e-53: 166: 97.62
+	Hs
		1216224 H2A2B_HUMAN (7-109): 2.22e-51: 160: 48.54		H2B3B_HUMAN (1-126): 6.16e-52: 161: 95.24
+	Hs
		1216241 H2A2B_HUMAN (7-109): 2.22e-51: 160: 48.54		H2B1A_HUMAN (1-126): 1.29e-46: 148: 85.04