HitPredict

Interactor 1: A0A8I3N6C6 (A0A8I3N6C6)
Rho GDP-dissociation inhibitor 1 (Rho-GDI alpha)
Gene: ARHGDIA

Interactor 2: RAC1 (P62999)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Rac2) (p21-Rac1)
Gene: RAC1

Species: Canis lupus familiaris

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	20160093
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Rho_GDI
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 160 Cl			1 192
+	Hs
		854769 GDIR1_HUMAN (1-160): 4.43e-74: 222: 76.47		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Mm
		925816 GDIR1_MOUSE (1-160): 3.44e-74: 222: 77.45		RAC1_MOUSE (1-192): 3.81e-86: 253: 100.00
+	Hs
		545278 GDIR1_HUMAN (1-160): 4.43e-74: 222: 76.47		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		854759 GDIR1_HUMAN (1-160): 4.43e-74: 222: 76.47		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		854771 GDIR1_HUMAN (1-160): 4.43e-74: 222: 76.47		RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35
+	Mm
		892716 GDIR1_MOUSE (1-160): 3.44e-74: 222: 77.45		RAC3_MOUSE (1-191): 2.72e-79: 236: 93.19
+	Hs
		854760 GDIR1_HUMAN (1-160): 4.43e-74: 222: 76.47		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Rn
		901290 GDIR1_RAT (1-160): 3.44e-74: 222: 77.45		RHOA_RAT (5-192): 1.43e-77: 231: 57.98
+	Hs
		854763 GDIR1_HUMAN (1-160): 4.43e-74: 222: 76.47		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		436218 GDIR1_HUMAN (1-160): 4.43e-74: 222: 76.47		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45
+	Hs
		925561 GDIR3_HUMAN (15-160): 2.33e-61: 190: 44.21		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		854851 GDIR2_HUMAN (23-160): 2.83e-59: 184: 53.30		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		545279 GDIR2_HUMAN (23-160): 2.83e-59: 184: 53.30		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		951270 GDIR3_HUMAN (15-160): 2.33e-61: 190: 44.21		RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35
+	Mm
		892713 GDIR2_MOUSE (13-160): 6.85e-61: 188: 49.48		RAC3_MOUSE (1-191): 2.72e-79: 236: 93.19
+	Hs
		894357 GDIR3_HUMAN (15-160): 2.33e-61: 190: 44.21		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		854847 GDIR2_HUMAN (23-160): 2.83e-59: 184: 53.30		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		854852 GDIR2_HUMAN (23-160): 2.83e-59: 184: 53.30		RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35
+	Hs
		900840 GDIR3_HUMAN (15-160): 2.33e-61: 190: 44.21		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	At
		1105129 GDIR_ARATH (2-146): 2.32e-53: 170: 36.67		RAC3_ARATH (2-180): 3.62e-72: 218: 65.92