HitPredict

Interactor 1: C1T9A (P0C862)
Complement C1q and tumor necrosis factor-related protein 9A (Complement C1q and tumor necrosis factor-related protein 9)
Gene: C1QTNF9

Interactor 2: COIA1 (P39060)
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1 (NC1)]
Gene: COL18A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Collagen~Collagen
Common GO terms	GO:0005576 - extracellular region GO:0005581 - collagen trimer
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 333 Hs			1 1754
+	Hs
		70507 C1T9B_HUMAN (1-332): 3.8e-88: 269: 97.89		COIA1_HUMAN (1-1754): 0: 1036: 99.60
+	Hs
		760557 C1QT1_HUMAN (154-329): 5.03e-49: 167: 28.65		COIA1_HUMAN (1-1754): 0: 1036: 99.60
+	Hs
		760534 Q4VAQ0_HUMAN (23-332): 2.13e-39: 145: 38.34		COIA1_HUMAN (1-1754): 0: 1036: 99.60
+	Hs
		626308 CO8A2_HUMAN (21-329): 3.15e-23: 102: 44.03		COIA1_HUMAN (1-1754): 0: 1036: 99.60
+	Hs
		441048 C1T9A_HUMAN (1-333): 6.9e-88: 268: 100.00		CO4A2_HUMAN (875-1671): 4.08e-60: 231: 24.21
+	Hs
		358667 C1QT1_HUMAN (154-329): 5.03e-49: 167: 28.65		CO4A1_HUMAN (783-1673): 7.78e-70: 262: 22.25
+	Hs
		441079 C1QT1_HUMAN (154-329): 5.03e-49: 167: 28.65		CO4A2_HUMAN (875-1671): 4.08e-60: 231: 24.21
+	Hs
		358641 C1QT1_HUMAN (154-329): 5.03e-49: 167: 28.65		CO3A1_HUMAN (594-1487): 3.12e-59: 227: 27.80
+	Hs
		70495 C1T9B_HUMAN (1-332): 3.8e-88: 269: 97.89		CO2A1_HUMAN (1236-1673): 2.7e-27: 123: 17.83
+	Hs
		358590 C1T9A_HUMAN (1-333): 6.9e-88: 268: 100.00		CO2A1_HUMAN (1236-1673): 2.7e-27: 123: 17.83
+	Hs
		441066 Q4VAQ0_HUMAN (23-332): 2.13e-39: 145: 38.34		CO4A2_HUMAN (875-1671): 4.08e-60: 231: 24.21
+	Hs
		441057 CO8A2_HUMAN (21-329): 3.15e-23: 102: 44.03		CO4A2_HUMAN (875-1671): 4.08e-60: 231: 24.21
+	Hs
		358617 C1QT1_HUMAN (154-329): 5.03e-49: 167: 28.65		CO2A1_HUMAN (1236-1673): 2.7e-27: 123: 17.83
+	Hs
		1047982 C1QT1_HUMAN (154-329): 5.03e-49: 167: 28.65		CO4A6_HUMAN (1192-1673): 6.92e-26: 118: 18.92
+	Hs
		358610 Q4VAQ0_HUMAN (23-332): 2.13e-39: 145: 38.34		CO2A1_HUMAN (1236-1673): 2.7e-27: 123: 17.83
+	Hs
		1047979 Q4VAQ0_HUMAN (23-332): 2.13e-39: 145: 38.34		CO4A6_HUMAN (1192-1673): 6.92e-26: 118: 18.92
+	Mm
		93247 E9PWQ3_MOUSE (8-231): 4.68e-49: 178: 29.44		E9PWQ3_MOUSE (1558-1684): 6.7e-12: 73.1: 10.53
+	Hs
		1299053 C1QT1_HUMAN (154-329): 5.03e-49: 167: 28.65		COLA1_HUMAN (1534-1672): 4.01e-15: 83.5: 10.79
+	Hs
		358599 CO8A2_HUMAN (21-329): 3.15e-23: 102: 44.03		CO2A1_HUMAN (1236-1673): 2.7e-27: 123: 17.83
+	Hs
		358479 CO8A2_HUMAN (21-329): 3.15e-23: 102: 44.03		CO1A1_HUMAN (614-901): 6.51e-11: 70.1: 24.83