HitPredict

Interactor 1: UBB (P0CG47)
Polyubiquitin-B [Cleaved into: Ubiquitin]
Gene: UBB

Interactor 2: PSMD4 (P55036)
26S proteasome non-ATPase regulatory subunit 4 (26S proteasome regulatory subunit RPN10) (26S proteasome regulatory subunit S5A) (Antisecretory factor 1) (AF) (ASF) (Multiubiquitin chain-binding protein)
Gene: PSMD4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	1.00	0.799

Property	Details
Experiments	28292943, 17662948
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	UIM~ubiquitin, VWA_2~ubiquitin
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 229 Hs			1 377
+	Mm
		192426 UBC_MOUSE (1-181): 6.49e-62: 207: 96.13		PSMD4_MOUSE (1-370): 0: 519: 96.22
+	Hs
		475528 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		PSMD4_HUMAN (1-364): 0: 530: 100.00
+	Hs
		874068 RS27A_HUMAN (153-228): 1.76e-44: 147: 100.00		PSMD4_HUMAN (1-364): 0: 530: 100.00
+	Hs
		171487 UBD_HUMAN (79-228): 1.03e-29: 110: 31.41		PSMD4_HUMAN (1-364): 0: 530: 100.00
+	Hs
		397868 ISG15_HUMAN (3-154): 1.46e-26: 102: 32.26		PSMD4_HUMAN (1-364): 0: 530: 100.00
+	At
		874015 UBQ3_ARATH (1-153): 2.79e-55: 180: 95.43		PSMD4_ARATH (1-377): 4.15e-138: 400: 41.32
+	Sc
		477277 UBI4P_YEAST (1-228): 5.66e-90: 271: 96.05		RPN10_YEAST (1-224): 1.27e-98: 295: 49.15
+	At
		874026 P4KG4_ARATH (83-224): 1.43e-22: 97.4: 36.55		PSMD4_ARATH (1-377): 4.15e-138: 400: 41.32