HitPredict

Interactor 1: UBB (P0CG47)
Polyubiquitin-B [Cleaved into: Ubiquitin]
Gene: UBB

Interactor 2: RNF11 (Q9Y3C5)
RING finger protein 11
Gene: RNF11

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	1.00	0.877

Property	Details
Experiments	28514442, 33961781, 14755250
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid
Interaction Type	physical association, ubiquitination reaction, association

Property	Details
Interacting Pfam domains	ubiquitin~zf-RING_2
Common GO terms	GO:0005634 - nucleus GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 229 Hs			1 154
+	Hs
		475090 UBB_HUMAN (1-229): 4.07e-98: 286: 100.00		GOLI_HUMAN (57-146): 1.98e-25: 101: 24.44
+	At
		477669 UBQ11_ARATH (1-228): 1.25e-94: 278: 96.05		Q9FM98_ARATH (9-153): 9.53e-24: 96.9: 21.05
+	At
		1210477 UBQ10_ARATH (1-228): 2.81e-91: 277: 96.05		Q9FM98_ARATH (9-153): 9.53e-24: 96.9: 21.05
+	Hs
		476612 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		RNF11_HUMAN (1-154): 1.51e-42: 140: 100.00
+	Hs
		1286324 Q96C32_HUMAN (1-153): 2.55e-56: 182: 99.35		RNF11_HUMAN (1-154): 1.51e-42: 140: 100.00
+	Mm
		476994 UBC_MOUSE (1-181): 6.49e-62: 207: 96.13		RN115_MOUSE (6-154): 8.96e-27: 103: 19.75
+	Mm
		476947 UBC_MOUSE (1-181): 6.49e-62: 207: 96.13		RN126_MOUSE (41-150): 2.67e-23: 94.6: 25.89
+	Mm
		477051 UBC_MOUSE (1-181): 6.49e-62: 207: 96.13		RNF12_MOUSE (41-146): 3.85e-21: 90.3: 25.47
+	Hs
		924226 RS27A_HUMAN (153-228): 1.76e-44: 147: 100.00		RNF11_HUMAN (1-154): 1.51e-42: 140: 100.00
+	Hs
		476628 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		RN115_HUMAN (10-154): 2e-26: 102: 19.08
+	At
		1091813 UBQ3_ARATH (1-153): 2.79e-55: 180: 95.43		RNG1L_ARATH (15-153): 5.68e-27: 104: 23.61
+	Hs
		476007 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		GOLI_HUMAN (57-146): 1.98e-25: 101: 24.44
+	At
		1092053 UBQ3_ARATH (1-153): 2.79e-55: 180: 95.43		Q9FM98_ARATH (9-153): 9.53e-24: 96.9: 21.05
+	Hs
		476458 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		RNF12_HUMAN (91-146): 1.14e-21: 91.8: 39.29
+	Hs
		924057 RS27A_HUMAN (153-228): 1.76e-44: 147: 100.00		GOLI_HUMAN (57-146): 1.98e-25: 101: 24.44
+	Hs
		1130024 Q5RKT7_HUMAN (77-153): 7.31e-23: 92.4: 98.70		RNF11_HUMAN (1-154): 1.51e-42: 140: 100.00
+	Hs
		398150 ISG15_HUMAN (3-154): 1.46e-26: 102: 32.26		RN115_HUMAN (10-154): 2e-26: 102: 19.08
+	Zm
		79051 B6SKC9_MAIZE (71-223): 1.81e-23: 99.7: 27.39		C0P544_MAIZE (14-143): 9.45e-26: 99.1: 24.44