HitPredict

Interactor 1: UBB (P0CG47)
Polyubiquitin-B [Cleaved into: Ubiquitin]
Gene: UBB

Interactor 2: KC1G3 (Q9Y6M4)
Casein kinase I isoform gamma-3 (CKI-gamma 3) (EC 2.7.11.1)
Gene: CSNK1G3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 229 Hs			1 447
+	Hs
		474936 UBB_HUMAN (1-229): 4.07e-98: 286: 100.00		AKT2_HUMAN (1-386): 6.22e-125: 373: 18.37
+	Hs
		474935 UBB_HUMAN (1-229): 4.07e-98: 286: 100.00		AKT1_HUMAN (4-386): 2.58e-122: 366: 19.74
+	Hs
		474923 UBB_HUMAN (1-229): 4.07e-98: 286: 100.00		KAPCG_HUMAN (2-370): 4.98e-120: 355: 18.67
+	Rn
		956857 UBC_RAT (1-181): 2.6e-61: 206: 96.13		KC1A_RAT (28-340): 6.1e-129: 377: 52.23
+	Rn
		448416 UBC_RAT (1-181): 2.6e-61: 206: 96.13		KPCE_RAT (7-386): 1.31e-117: 362: 15.54
+	Rn
		1144021 UBC_RAT (1-181): 2.6e-61: 206: 96.13		KC1G1_RAT (1-385): 3.36e-117: 349: 76.35
+	Hs
		475390 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		AKT1_HUMAN (4-386): 2.58e-122: 366: 19.74
+	At
		1091642 UBQ3_ARATH (1-153): 2.79e-55: 180: 95.43		CDPKB_ARATH (18-398): 6.17e-118: 355: 15.50
+	Hs
		821976 RS27A_HUMAN (153-228): 1.76e-44: 147: 100.00		KC1A_HUMAN (28-364): 3.67e-130: 381: 50.59
+	Hs
		681773 RS27A_HUMAN (153-228): 1.76e-44: 147: 100.00		AKT1_HUMAN (4-386): 2.58e-122: 366: 19.74
+	Hs
		923962 RS27A_HUMAN (153-228): 1.76e-44: 147: 100.00		KPCE_HUMAN (7-386): 1.03e-117: 362: 15.54