HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: KPCA (P17252)
Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)
Gene: PRKCA

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	18566587
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 672
+	Hs
		408535 UBC_HUMAN (1-685): 0: 846: 100.00		KPCB_HUMAN (1-664): 0: 749: 78.89
+	Hs
		475390 UBC_HUMAN (1-685): 0: 846: 100.00		AKT1_HUMAN (243-660): 2.07e-155: 459: 37.36
+	Hs
		116959 UBC_HUMAN (1-685): 0: 846: 100.00		SGK1_HUMAN (255-661): 1.16e-153: 452: 38.85
+	Hs
		475450 UBC_HUMAN (1-685): 0: 846: 100.00		KPCI_HUMAN (22-86): 8.63e-12: 70.1: 43.08
+	Hs
		475653 UBC_HUMAN (1-685): 0: 846: 100.00		KPCZ_HUMAN (22-98): 3.2e-11: 68.6: 34.44
+	Rn
		934619 UBC_RAT (1-108): 1.27e-29: 127: 90.74		KPCB_RAT (1-664): 0: 747: 79.34
+	Hs
		408534 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		KPCB_HUMAN (1-664): 0: 749: 78.89
+	Rn
		930581 UBC_RAT (1-108): 1.27e-29: 127: 90.74		KPCG_RAT (16-670): 0: 698: 69.88
+	Hs
		923962 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		KPCE_HUMAN (8-664): 0: 635: 44.61
+	Rn
		448416 UBC_RAT (1-108): 1.27e-29: 127: 90.74		KPCE_RAT (8-664): 0: 631: 44.31
+	Hs
		681773 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		AKT1_HUMAN (243-660): 2.07e-155: 459: 37.36
+	Hs
		474935 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		AKT1_HUMAN (243-660): 2.07e-155: 459: 37.36
+	Hs
		474936 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		AKT2_HUMAN (242-660): 9.73e-156: 459: 39.13
+	Rn
		448410 UBC_RAT (1-108): 1.27e-29: 127: 90.74		KPCD_RAT (9-175): 2.83e-56: 204: 37.29
+	Mm
		476830 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		KPCI_MOUSE (22-108): 6.42e-34: 139: 36.78