HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: SFPQ (P23246)
Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)
Gene: SFPQ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.647

Property	Details
Experiments	16169070, 16196087, 23314748
Identification Methods	two hybrid, affinity chromatography technology, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 707
+	Hs
		475708 UBC_HUMAN (1-685): 0: 846: 100.00		PABP4_HUMAN (287-694): 8.34e-83: 277: 17.38
+	Hs
		475288 UBC_HUMAN (1-685): 0: 846: 100.00		PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46
+	At
		983451 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		PABP5_ARATH (245-697): 1.47e-55: 203: 15.39
+	At
		186465 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		PABP4_ARATH (238-661): 2.94e-37: 150: 12.56
+	Rn
		1144257 UBC_RAT (1-108): 1.27e-29: 127: 90.74		PABP1_RAT (287-700): 1.75e-72: 249: 16.67
+	Mm
		476693 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		PABP1_MOUSE (287-700): 2.49e-70: 243: 16.67
+	Hs
		1031342 OASL_HUMAN (1-153): 6.51e-17: 86.3: 29.11		PABP4_HUMAN (287-694): 8.34e-83: 277: 17.38
+	Hs
		474924 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		SFPQ_HUMAN (1-707): 4.51e-74: 255: 100.00
+	Hs
		397745 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46
+	Hs
		516533 OASL_HUMAN (1-153): 6.51e-17: 86.3: 29.11		PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46