HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: DNJB2 (P25686)
DnaJ homolog subfamily B member 2 (Heat shock 40 kDa protein 3) (Heat shock protein J1) (HSJ-1)
Gene: DNAJB2

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.679

Property	Details
Experiments	38803224, 19285159, 15936278
Identification Methods	pull down, affinity chromatography technology, two hybrid, protein array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 324
+	Hs
		257894 UBC_HUMAN (1-685): 0: 846: 100.00		DNJB6_HUMAN (1-283): 7.47e-82: 252: 47.63
+	Hs
		475355 UBC_HUMAN (1-685): 0: 846: 100.00		DNJB1_HUMAN (2-161): 3.26e-43: 153: 40.63
+	Hs
		636473 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		DNJB2_HUMAN (1-324): 1.9e-125: 363: 100.00
+	Mm
		477042 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		DNJB2_MOUSE (1-324): 9.33e-127: 366: 85.19
+	Hs
		397783 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		DNJB2_HUMAN (1-324): 1.9e-125: 363: 100.00
+	Hs
		474929 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		DNJB2_HUMAN (1-324): 1.9e-125: 363: 100.00
+	At
		1012787 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		Q0WN54_ARATH (3-238): 1.64e-42: 155: 25.10
+	At
		67521 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		A8MR40_ARATH (2-105): 2.09e-42: 149: 50.45
+	Rn
		88985 UBC_RAT (1-108): 1.27e-29: 127: 90.74		D4ABC2_RAT (1-274): 6.62e-93: 278: 82.48
+	Hs
		257885 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		DNJB6_HUMAN (1-283): 7.47e-82: 252: 47.63
+	Mm
		222718 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		DNJB6_MOUSE (1-273): 4.6e-75: 236: 41.28
+	Mm
		93712 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		DJC21_MOUSE (1-317): 1.74e-68: 224: 22.12
+	Rn
		1140400 UBC_RAT (1-108): 1.27e-29: 127: 90.74		Q5XIP0_RAT (2-239): 7.23e-45: 157: 28.05
+	Hs
		279269 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		DNJB5_HUMAN (2-239): 5.52e-44: 155: 25.88
+	Hs
		398129 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		DNJB4_HUMAN (2-238): 5.01e-44: 155: 28.98
+	Hs
		397782 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		DNJB1_HUMAN (2-161): 3.26e-43: 153: 40.63
+	Hs
		1076133 OASL_HUMAN (1-153): 6.51e-17: 86.3: 29.11		DJB11_HUMAN (2-228): 1.38e-51: 175: 27.31