HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: PSA1 (P25786)
Proteasome subunit alpha type-1 (30 kDa prosomal protein) (PROS-30) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome component C2) (Proteasome nu chain)
Gene: PSMA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16196087
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 263
+	Hs
		156205 UBC_HUMAN (1-685): 0: 846: 100.00		PSA7_HUMAN (6-234): 9.99e-96: 282: 33.19
+	Hs
		475369 UBC_HUMAN (1-685): 0: 846: 100.00		PSA5_HUMAN (1-236): 5.66e-93: 275: 28.81
+	Hs
		475547 UBC_HUMAN (1-685): 0: 846: 100.00		PSA6_HUMAN (1-240): 1.64e-92: 274: 25.00
+	At
		189234 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		PSA7B_ARATH (4-233): 4.98e-96: 283: 32.34
+	At
		188704 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		PSA1B_ARATH (1-240): 1.35e-94: 280: 50.00
+	At
		709289 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		PSA1A_ARATH (1-238): 1.05e-93: 278: 50.00
+	At
		188696 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		PSA2A_ARATH (1-237): 1.71e-93: 276: 32.64
+	At
		1091773 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		PSA2B_ARATH (1-237): 1.1e-92: 274: 32.64
+	At
		286456 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		PSA4A_ARATH (1-245): 1.92e-91: 272: 28.85
+	At
		286449 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		PSA6A_ARATH (1-240): 4.34e-91: 270: 29.03
+	Hs
		637385 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		PSA1_HUMAN (1-263): 3.26e-109: 317: 100.00
+	Mm
		477050 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		PSA1_MOUSE (1-263): 2.54e-109: 317: 98.10
+	Rn
		576260 UBC_RAT (1-108): 1.27e-29: 127: 90.74		PSA1_RAT (1-263): 2.14e-108: 315: 97.72
+	Hs
		397785 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		PSA1_HUMAN (1-263): 3.26e-109: 317: 100.00
+	Hs
		893645 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		PSA6_HUMAN (1-240): 1.64e-92: 274: 25.00
+	Hs
		638108 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		PSA4_HUMAN (1-233): 4.82e-91: 271: 28.75
+	At
		672527 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		PSA7A_ARATH (5-218): 8.98e-37: 132: 35.32
+	Rn
		893780 UBC_RAT (1-108): 1.27e-29: 127: 90.74		PSA6_RAT (1-240): 1.64e-92: 274: 25.00
+	Hs
		156201 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		PSA7_HUMAN (6-234): 9.99e-96: 282: 33.19
+	Hs
		397788 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		PSA4_HUMAN (1-233): 4.82e-91: 271: 28.75