HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: PRDX3 (P30048)
Thioredoxin-dependent peroxide reductase, mitochondrial (EC 1.11.1.24) (Antioxidant protein 1) (AOP-1) (HBC189) (Peroxiredoxin III) (Prx-III) (Peroxiredoxin-3) (Protein MER5 homolog) (Thioredoxin-dependent peroxiredoxin 3)
Gene: PRDX3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27182664
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 256
+	Hs
		475394 UBC_HUMAN (1-685): 0: 846: 100.00		PRDX2_HUMAN (58-255): 2.07e-104: 302: 63.13
+	Hs
		475698 UBC_HUMAN (1-685): 0: 846: 100.00		PRDX4_HUMAN (35-255): 3.38e-103: 302: 58.82
+	Hs
		475659 UBC_HUMAN (1-685): 0: 846: 100.00		PRDX1_HUMAN (63-253): 1.5e-100: 293: 63.54
+	Hs
		475376 UBC_HUMAN (1-685): 0: 846: 100.00		PRDX6_HUMAN (63-254): 3.4e-68: 211: 25.25
+	At
		1091947 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		BAS1A_ARATH (53-254): 5.79e-94: 278: 53.43
+	Hs
		923973 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		PRDX4_HUMAN (35-255): 3.38e-103: 302: 58.82
+	Rn
		1144159 UBC_RAT (1-108): 1.27e-29: 127: 90.74		PRDX1_RAT (63-253): 5.84e-101: 293: 63.02
+	Hs
		474937 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		PRDX2_HUMAN (58-255): 2.07e-104: 302: 63.13
+	Hs
		397928 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		PRDX1_HUMAN (63-253): 1.5e-100: 293: 63.54
+	Hs
		397803 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		PRDX6_HUMAN (63-254): 3.4e-68: 211: 25.25