HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: UBP6 (P35125)
Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.4.19.12) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2) (RN-tre) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6)
Gene: USP6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	29576527
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UCH~ubiquitin
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 1406
+	Hs
		476067 UBC_HUMAN (1-685): 0: 846: 100.00		UBP32_HUMAN (484-1406): 0: 695: 92.52
+	Hs
		475693 UBC_HUMAN (1-685): 0: 846: 100.00		UBP4_HUMAN (1194-1373): 1.34e-26: 120: 16.58
+	Hs
		475502 UBC_HUMAN (1-685): 0: 846: 100.00		UBP11_HUMAN (1206-1379): 2.52e-26: 119: 17.05
+	Hs
		301354 UBC_HUMAN (1-685): 0: 846: 100.00		UBP19_HUMAN (1210-1389): 8.43e-25: 114: 15.96
+	Hs
		475954 UBC_HUMAN (1-685): 0: 846: 100.00		UBP31_HUMAN (1198-1376): 3.74e-24: 112: 18.59
+	Hs
		476624 UBC_HUMAN (1-685): 0: 846: 100.00		UBP15_HUMAN (1129-1373): 1.48e-22: 107: 15.85
+	Hs
		475440 UBC_HUMAN (1-685): 0: 846: 100.00		UBP8_HUMAN (1026-1111): 1.38e-10: 68.2: 37.21
+	Hs
		271022 UBC_HUMAN (1-685): 0: 846: 100.00		UBP2_HUMAN (1311-1367): 5.38e-09: 62.8: 46.55
+	Mm
		101489 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		UBP32_MOUSE (484-1406): 0: 674: 88.73
+	Sc
		477284 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		UBP12_YEAST (1191-1374): 2.81e-20: 100: 21.08
+	Rn
		70290 UBC_RAT (1-108): 1.27e-29: 127: 90.74		UBP4_RAT (1194-1399): 3.18e-28: 125: 18.40
+	Mm
		476695 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		UBP4_MOUSE (1194-1399): 1.68e-27: 123: 17.93
+	Mm
		476963 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		UBP11_MOUSE (1218-1392): 2.11e-26: 119: 19.13
+	Mm
		476793 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		UBP19_MOUSE (1210-1387): 4.66e-25: 115: 16.67
+	Mm
		476926 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		UBP15_MOUSE (1217-1373): 2.8e-22: 106: 22.79
+	Mm
		476865 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		UBP8_MOUSE (1026-1111): 1.7e-10: 68.2: 37.21
+	Hs
		271114 Q5U5U6_HUMAN (1-77): 7.83e-26: 108: 98.70		UBP2_HUMAN (1311-1367): 5.38e-09: 62.8: 46.55