HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	20601937, 19233177
Identification Methods	pull down, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ubiquitin~zf-C3HC4_2
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 326
+	Hs
		475406 UBC_HUMAN (1-685): 0: 846: 100.00		PCGF2_HUMAN (1-320): 1.04e-117: 344: 61.36
+	Hs
		475328 UBC_HUMAN (1-685): 0: 846: 100.00		RO52_HUMAN (5-198): 5.75e-52: 180: 18.78
+	Hs
		475680 UBC_HUMAN (1-685): 0: 846: 100.00		TRI26_HUMAN (5-210): 1e-49: 175: 16.59
+	Hs
		476254 UBC_HUMAN (1-685): 0: 846: 100.00		RING2_HUMAN (7-227): 8.37e-50: 170: 16.61
+	Hs
		476330 UBC_HUMAN (1-685): 0: 846: 100.00		TRIM5_HUMAN (9-190): 3.01e-48: 170: 14.89
+	Hs
		476418 UBC_HUMAN (1-685): 0: 846: 100.00		TRI39_HUMAN (9-198): 1.36e-45: 163: 16.50
+	Hs
		476635 UBC_HUMAN (1-685): 0: 846: 100.00		TRI17_HUMAN (10-198): 2.34e-44: 159: 15.42
+	Hs
		475658 UBC_HUMAN (1-685): 0: 846: 100.00		RING1_HUMAN (7-115): 2.38e-30: 120: 25.46
+	Hs
		282497 UBC_HUMAN (1-685): 0: 846: 100.00		RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00
+	Xl
		1125746 Q7SY79_XENLA (77-685): 0: 744: 99.84		CHFR_XENLA (3-152): 1.29e-33: 132: 19.87
+	Mm
		476671 UBB_MOUSE (457-685): 2.3e-86: 275: 99.56		RO52_MOUSE (3-192): 1.62e-52: 181: 17.28
+	Mm
		924236 RS27A_MOUSE (609-684): 9.1e-41: 147: 100.00		RO52_MOUSE (3-192): 1.62e-52: 181: 17.28
+	Mm
		476831 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RO52_MOUSE (3-192): 1.62e-52: 181: 17.28
+	Hs
		475177 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		TRIM5_HUMAN (9-190): 3.01e-48: 170: 14.89
+	Xl
		923941 UBIQP_XENLA (594-685): 1.96e-29: 116: 98.91		CHFR_XENLA (3-152): 1.29e-33: 132: 19.87