HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: EPS15 (P42566)
Epidermal growth factor receptor substrate 15 (Protein Eps15) (Protein AF-1p)
Gene: EPS15

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.751

Property	Details
Experiments	16429130, 28190767, 31699778, 36114200, 38803224, 19880507, 28082312, 17013377, 19380743
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 896
+	Hs
		476483 UBC_HUMAN (1-685): 0: 846: 100.00		ITSN2_HUMAN (3-845): 2.31e-61: 229: 14.40
+	Hs
		475816 UBC_HUMAN (1-685): 0: 846: 100.00		ITSN1_HUMAN (2-520): 3.13e-38: 157: 14.61
+	Hs
		475882 UBC_HUMAN (1-685): 0: 846: 100.00		FKB15_HUMAN (76-873): 1.31e-37: 154: 11.35
+	Hs
		476502 UBC_HUMAN (1-685): 0: 846: 100.00		EP15R_HUMAN (417-891): 5.86e-14: 78.3: 11.98
+	Mm
		476700 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		EPS15_MOUSE (1-896): 6.54e-132: 419: 88.54
+	Rn
		1126748 UBC_RAT (1-108): 1.27e-29: 127: 90.74		Q5JC29_RAT (1-774): 7.44e-120: 384: 88.79
+	Sc
		477209 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		EDE1_YEAST (3-327): 3e-15: 82.9: 24.01
+	Sc
		477280 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		END3_YEAST (15-378): 4.53e-13: 73.6: 17.73
+	Mm
		70590 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		B2RR82_MOUSE (3-813): 3.1e-64: 238: 14.63
+	Mm
		477062 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		ITSN1_MOUSE (2-737): 1.82e-38: 158: 11.80
+	Rn
		1144238 UBC_RAT (1-108): 1.27e-29: 127: 90.74		Q8R3Z7_RAT (213-318): 3.04e-11: 68.9: 38.68
+	Rn
		88639 UBC_RAT (1-108): 1.27e-29: 127: 90.74		D3ZJR1_RAT (431-895): 6.08e-11: 68.7: 10.71
+	Mm
		476822 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		EP15R_MOUSE (417-895): 9.06e-11: 67.9: 12.27