HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: PSA6 (P60900)
Proteasome subunit alpha type-6 (27 kDa prosomal protein) (PROS-27) (p27K) (Macropain iota chain) (Multicatalytic endopeptidase complex iota chain) (Proteasome iota chain)
Gene: PSMA6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	30659753, 16196087
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 246
+	Hs
		475359 UBC_HUMAN (1-685): 0: 846: 100.00		PSA2_HUMAN (7-243): 8.3e-104: 302: 35.44
+	Hs
		156205 UBC_HUMAN (1-685): 0: 846: 100.00		PSA7_HUMAN (9-240): 1.34e-97: 286: 33.62
+	Hs
		475369 UBC_HUMAN (1-685): 0: 846: 100.00		PSA5_HUMAN (1-242): 4.79e-96: 282: 25.91
+	Hs
		475358 UBC_HUMAN (1-685): 0: 846: 100.00		PSA1_HUMAN (1-245): 2.4e-94: 279: 25.91
+	At
		286449 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		PSA6A_ARATH (1-246): 5.56e-109: 315: 64.23
+	At
		286452 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		PSA6B_ARATH (1-246): 9.62e-105: 305: 62.60
+	At
		189234 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		PSA7B_ARATH (7-239): 1.44e-95: 281: 35.04
+	At
		286456 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		PSA4A_ARATH (6-241): 1.09e-93: 276: 32.78
+	At
		672527 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		PSA7A_ARATH (7-236): 2.44e-93: 276: 34.63
+	Sc
		477138 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		PSA3_YEAST (6-203): 6.44e-40: 140: 37.19
+	Hs
		893645 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		PSA6_HUMAN (1-246): 2.11e-110: 319: 100.00
+	Rn
		893780 UBC_RAT (1-108): 1.27e-29: 127: 90.74		PSA6_RAT (1-246): 2.11e-110: 319: 100.00
+	Rn
		566254 UBC_RAT (1-108): 1.27e-29: 127: 90.74		PSA2_RAT (7-243): 1.62e-103: 301: 35.44
+	Hs
		637385 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		PSA1_HUMAN (1-245): 2.4e-94: 279: 25.91
+	Hs
		638108 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		PSA4_HUMAN (6-239): 5.7e-93: 275: 32.35
+	At
		1091773 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		PSA2B_ARATH (13-239): 2.13e-42: 145: 35.68
+	At
		188696 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		PSA2A_ARATH (13-239): 2.09e-42: 145: 35.68
+	Mm
		477050 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		PSA1_MOUSE (1-245): 2.1e-94: 279: 25.91
+	Rn
		576260 UBC_RAT (1-108): 1.27e-29: 127: 90.74		PSA1_RAT (1-245): 5.74e-94: 278: 26.32
+	Hs
		156201 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		PSA7_HUMAN (9-240): 1.34e-97: 286: 33.62