Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: UBE2N (P61088)
Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubc13) (UbcH13) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N)
Gene: UBE2N

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.990

The method score is based on:

Property Details
Experiments 22325355, 17964296, 23105008, 11504715, 29950522, 29667579, 30342007, 30884854, 27182664, 31638574, 32488130, 30420781, 36831384, 24361330, 38803224, 20613989, 14517261, 12569095, 22367539, 12847084 and 3 others

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Identification Methods enzymatic study, pull down, x-ray crystallography, proximity labelling technology, affinity chromatography technology
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains UQ_con~ubiquitin
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0016567 - protein ubiquitination
and 2 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 685
Hs

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Last updated: 15 Jul 2024