HitPredict

Interactor 1: A0A8M9PHF0 (A0A8M9PHF0)
receptor protein-tyrosine kinase (EC 2.7.10.1)
Gene: epha7

Interactor 2: EFNB2 (O73874)
Ephrin-B2a
Gene: efnb2a

Species: Danio rerio

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26190107
Identification Methods	avexis
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ephrin~Ephrin_lbd
Common GO terms	GO:0005886 - plasma membrane GO:0007411 - axon guidance GO:0048013 - ephrin receptor signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 990 Dr			1 332
+	Hs
		957840 EPHA7_HUMAN (10-990): 0: 1254: 87.46		EFNB1_HUMAN (6-332): 7.83e-165: 464: 51.01
+	Dr
		251124 Q5ZEW1_DANRE (13-990): 0: 1231: 61.57		EFNB2_DANRE (1-332): 2.14e-165: 465: 100.00
+	Mm
		856591 EPHA4_MOUSE (13-990): 0: 1209: 62.49		EFNB2_MOUSE (3-332): 1.41e-165: 466: 65.56
+	Hs
		856508 EPHA5_HUMAN (14-980): 0: 1207: 62.16		EFNB2_HUMAN (3-332): 8.51e-165: 464: 65.56
+	Dr
		1140993 Q5ZEW1_DANRE (13-990): 0: 1231: 61.57		Q90Z31_DANRE (12-332): 1.07e-139: 400: 48.02
+	Dr
		47531 A0A8M9PHF0_DANRE (1-990): 0: 1283: 100.00		A0A8M1Q1X6_DANRE (9-209): 8.39e-65: 205: 23.45
+	Dr
		47567 A0A8M9PHF0_DANRE (1-990): 0: 1283: 100.00		Q90YC5_DANRE (27-208): 1.98e-64: 204: 26.20
+	Dr
		47566 A0A8M9PHF0_DANRE (1-990): 0: 1283: 100.00		EFNA5_DANRE (11-192): 1.42e-63: 203: 25.76
+	Dr
		47565 A0A8M9PHF0_DANRE (1-990): 0: 1283: 100.00		EFNA2_DANRE (26-179): 1.54e-55: 181: 27.85
+	Hs
		856606 EPHA7_HUMAN (10-990): 0: 1254: 87.46		EFNA5_HUMAN (12-196): 3.78e-65: 206: 23.76
+	Mm
		139053 EPHA7_MOUSE (10-990): 0: 1249: 87.06		EFNA5_MOUSE (12-196): 3.25e-65: 207: 23.76
+	Hs
		856319 EPHA7_HUMAN (10-990): 0: 1254: 87.46		EFNA3_HUMAN (26-213): 1.35e-59: 193: 21.29
+	Dr
		47532 Q5ZEW1_DANRE (13-990): 0: 1231: 61.57		A0A8M1Q1X6_DANRE (9-209): 8.39e-65: 205: 23.45
+	Dr
		1140992 Q5ZEW1_DANRE (13-990): 0: 1231: 61.57		Q90YC5_DANRE (27-208): 1.98e-64: 204: 26.20
+	Dr
		945416 Q5ZEW1_DANRE (13-990): 0: 1231: 61.57		EFNA5_DANRE (11-192): 1.42e-63: 203: 25.76
+	Hs
		856385 EPHA7_HUMAN (10-990): 0: 1254: 87.46		EFNA4_HUMAN (9-193): 9.51e-53: 174: 24.06
+	Hs
		217642 EPHA7_HUMAN (10-990): 0: 1254: 87.46		EFNA2_HUMAN (26-157): 3.89e-48: 162: 29.58
+	Hs
		856595 EPHA5_HUMAN (14-980): 0: 1207: 62.16		EFNA5_HUMAN (12-196): 3.78e-65: 206: 23.76
+	Dr
		945415 Q5ZEW1_DANRE (13-990): 0: 1231: 61.57		EFNA2_DANRE (26-179): 1.54e-55: 181: 27.85
+	Hs
		217636 EPHA4_HUMAN (9-990): 0: 1205: 62.37		EFNA2_HUMAN (26-157): 3.89e-48: 162: 29.58