HitPredict

Interactor 1: A0A8M9PLL4 (A0A8M9PLL4)
Leucine-rich repeat transmembrane protein FLRT1
Gene: flrt1a

Interactor 2: A9JR35 (A9JR35)
Netrin receptor UNC5
Gene: unc5b

Species: Danio rerio

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.80	0.721

Property	Details
Experiments	26190107, 19765300
Identification Methods	avexis, solid phase assay, surface plasmon resonance
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	I-set~LRR_8, LRR_8~TSP_1
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 692 Dr			1 940
+	Dr
		69122 F1QF54_DANRE (41-692): 2.73e-129: 400: 67.71		A9JR35_DANRE (1-940): 0: 868: 100.00
+	Hs
		1224475 FLRT3_HUMAN (16-692): 1.78e-122: 381: 44.40		UNC5B_HUMAN (28-940): 0: 861: 66.67
+	Dr
		69121 B8A507_DANRE (21-692): 1.9e-118: 370: 46.02		A9JR35_DANRE (1-940): 0: 868: 100.00
+	Mm
		1206871 FLRT2_MOUSE (28-692): 1.53e-114: 360: 37.72		UNC5B_MOUSE (29-940): 0: 853: 66.74
+	Mm
		139751 FLRT2_MOUSE (28-692): 1.53e-114: 360: 37.72		UNC5C_MOUSE (14-939): 0: 835: 58.56
+	Mm
		1206872 FLRT2_MOUSE (28-692): 1.53e-114: 360: 37.72		UNC5A_MOUSE (8-940): 0: 806: 51.34
+	Mm
		1206870 FLRT2_MOUSE (28-692): 1.53e-114: 360: 37.72		UNC5D_MOUSE (35-939): 0: 745: 48.58
+	Hs
		195862 FLRT2_HUMAN (28-692): 5.86e-113: 356: 37.26		UNC5D_HUMAN (36-939): 0: 732: 48.31
+	Mm
		1164192 FLRT1_MOUSE (27-216): 1.31e-19: 95.6: 23.12		UNC5B_MOUSE (29-940): 0: 853: 66.74
+	Mm
		139750 FLRT1_MOUSE (27-216): 1.31e-19: 95.6: 23.12		UNC5C_MOUSE (14-939): 0: 835: 58.56
+	Mm
		1164193 FLRT1_MOUSE (27-216): 1.31e-19: 95.6: 23.12		UNC5A_MOUSE (8-940): 0: 806: 51.34
+	Mm
		1164191 FLRT1_MOUSE (27-216): 1.31e-19: 95.6: 23.12		UNC5D_MOUSE (35-939): 0: 745: 48.58
+	Dr
		47580 B8JKM0_DANRE (1-465): 5.96e-70: 239: 21.14		A0A8M9QLH5_DANRE (20-590): 2.21e-37: 154: 11.35
+	Dr
		82309 B8JKM0_DANRE (1-465): 5.96e-70: 239: 21.14		Q90Z70_DANRE (20-590): 2.67e-37: 154: 11.47
+	Dr
		94546 F1Q7Y5_DANRE (59-218): 1.78e-15: 82.6: 21.89		F1QFK4_DANRE (1-600): 5.41e-63: 234: 13.61
+	Mm
		1194740 LRC4C_MOUSE (53-230): 9.28e-14: 76.8: 15.51		AGRB3_MOUSE (202-410): 2.35e-41: 167: 25.93
+	Mm
		991210 FLRT1_MOUSE (27-216): 1.31e-19: 95.6: 23.12		CNTN3_MOUSE (21-591): 5.26e-34: 143: 11.50
+	Dr
		65449 F1Q7Y5_DANRE (59-218): 1.78e-15: 82.6: 21.89		A8DZ85_DANRE (11-244): 2.12e-28: 125: 15.98
+	Hs
		434617 PGS1_HUMAN (149-297): 3.67e-11: 67.4: 32.89		TSP1_HUMAN (190-438): 6.07e-17: 88.4: 18.40
+	Mm
		1112554 LRC4C_MOUSE (53-230): 9.28e-14: 76.8: 15.51		AGRB1_MOUSE (209-303): 1.14e-11: 71.4: 28.28