HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: CACO2 (Q13137)
Calcium-binding and coiled-coil domain-containing protein 2 (Antigen nuclear dot 52 kDa protein) (Nuclear domain 10 protein NDP52) (Nuclear domain 10 protein 52) (Nuclear dot protein 52)
Gene: CALCOCO2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	0.60	0.756

Property	Details
Experiments	26451915, 26506893, 25969509, 36114200, 25416956, 30853401, 32476569, 19285159, 31515488
Identification Methods	pull down, x-ray crystallography, affinity chromatography technology, two hybrid, protein array, two hybrid array
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 446
+	Hs
		476001 UBC_HUMAN (1-685): 0: 846: 100.00		TAXB1_HUMAN (13-437): 1.11e-40: 156: 21.87
+	Hs
		476091 UBC_HUMAN (1-685): 0: 846: 100.00		DLG5_HUMAN (77-439): 7.24e-18: 88.6: 10.03
+	Hs
		476502 UBC_HUMAN (1-685): 0: 846: 100.00		EP15R_HUMAN (76-252): 1.67e-15: 80.9: 15.25
+	Hs
		475882 UBC_HUMAN (1-685): 0: 846: 100.00		FKB15_HUMAN (128-441): 4.96e-13: 73.6: 9.49
+	Hs
		475644 UBC_HUMAN (1-685): 0: 846: 100.00		CENPE_HUMAN (124-345): 3.98e-10: 64.4: 21.34
+	Hs
		475452 UBC_HUMAN (1-685): 0: 846: 100.00		EPS15_HUMAN (77-234): 4.48e-10: 64: 11.88
+	Hs
		475417 UBC_HUMAN (1-685): 0: 846: 100.00		MYH9_HUMAN (144-345): 7.94e-09: 60.2: 15.05
+	Hs
		1025496 Q96C32_HUMAN (229-533): 1.87e-118: 358: 99.67		CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00
+	Hs
		923972 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00
+	Hs
		924056 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		TAXB1_HUMAN (13-437): 1.11e-40: 156: 21.87
+	Mm
		476794 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		TAXB1_MOUSE (13-439): 3.84e-36: 143: 21.23
+	Mm
		476822 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		EP15R_MOUSE (102-435): 2.36e-31: 129: 13.55
+	Rn
		88639 UBC_RAT (1-108): 1.27e-29: 127: 90.74		D3ZJR1_RAT (102-435): 5.71e-30: 125: 13.18
+	Mm
		476700 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		EPS15_MOUSE (75-249): 5.43e-10: 63.6: 11.11
+	Mm
		476930 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		MYH9_MOUSE (144-345): 5.01e-09: 61: 15.05
+	Rn
		1126748 UBC_RAT (1-108): 1.27e-29: 127: 90.74		Q5JC29_RAT (77-225): 3.69e-09: 60.9: 9.93
+	Mm
		476828 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		MYH10_MOUSE (60-417): 4.81e-09: 60.9: 12.06
+	Hs
		398052 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		MY18A_HUMAN (127-365): 3.21e-10: 64.8: 15.81
+	Hs
		397814 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		MYH10_HUMAN (60-417): 3.37e-09: 61.3: 12.06
+	Hs
		397813 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		MYH9_HUMAN (144-345): 7.94e-09: 60.2: 15.05