HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: ITSN1 (Q15811)
Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17)
Gene: ITSN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	38803224
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	SH3_1~ubiquitin, SH3_9~ubiquitin
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 1721
+	Hs
		476483 UBC_HUMAN (1-685): 0: 846: 100.00		ITSN2_HUMAN (1-1720): 0: 723: 54.73
+	Hs
		475282 UBC_HUMAN (1-685): 0: 846: 100.00		BCR_HUMAN (732-1682): 1.5e-71: 266: 12.45
+	Hs
		475982 UBC_HUMAN (1-685): 0: 846: 100.00		FGD2_HUMAN (1168-1690): 3.38e-70: 251: 17.78
+	Mm
		477062 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		ITSN1_MOUSE (1-1721): 0: 864: 94.54
+	Hs
		476502 UBC_HUMAN (1-685): 0: 846: 100.00		EP15R_HUMAN (545-929): 2.95e-11: 70.8: 14.14
+	Hs
		475452 UBC_HUMAN (1-685): 0: 846: 100.00		EPS15_HUMAN (529-913): 1.04e-10: 68.9: 12.69
+	Mm
		70590 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		B2RR82_MOUSE (1-1720): 0: 725: 54.27
+	Sc
		477209 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		EDE1_YEAST (105-331): 8.22e-13: 76.1: 21.52
+	Hs
		924052 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		ARHG8_HUMAN (1205-1573): 1.76e-75: 265: 25.95
+	Mm
		476700 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		EPS15_MOUSE (14-484): 1.37e-37: 156: 16.77
+	Mm
		476822 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		EP15R_MOUSE (183-623): 8.62e-31: 134: 19.46
+	Rn
		88639 UBC_RAT (1-108): 1.27e-29: 127: 90.74		D3ZJR1_RAT (181-623): 2e-30: 133: 18.54
+	Hs
		924030 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		ARHGG_HUMAN (1224-1491): 2.63e-20: 99.8: 29.18
+	Rn
		102529 UBC_RAT (1-108): 1.27e-29: 127: 90.74		G3V856_RAT (1227-1491): 9.22e-22: 103: 28.47
+	Hs
		557653 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		NCK1_HUMAN (895-1055): 6.44e-09: 62: 27.75
+	Rn
		1126748 UBC_RAT (1-108): 1.27e-29: 127: 90.74		Q5JC29_RAT (529-841): 5.46e-10: 66.6: 12.00