Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: NEDD8 (Q15843)
NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8) (Ubiquitin-like protein Nedd8)
Gene: NEDD8

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.912

The method score is based on:

Property Details
Experiments 23105008, 16196087, 21145461, 19782077, 18274552
Identification Methods pull down, x-ray crystallography, affinity chromatography technology, enzymatic study, tandem affinity purification
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ubiquitin~ubiquitin
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0019941 - modification-dependent protein catabolic process
GO:0031386 - protein tag activity
and 2 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 685
Hs

1 81
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024