HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: ADRM1 (Q16186)
Proteasomal ubiquitin receptor ADRM1 (110 kDa cell membrane glycoprotein) (Gp110) (Adhesion-regulating molecule 1) (ARM-1) (Proteasome regulatory particle non-ATPase 13) (hRpn13) (Rpn13 homolog)
Gene: ADRM1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	1.00	0.975

Property	Details
Experiments	18497817, 25702870, 27396824, 30664872, 32857986, 18497827, 24361330, 28190767, 31699778, 23153250, 20059542
Identification Methods	two hybrid, pull down, x-ray crystallography
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	Proteasom_Rpn13~ubiquitin, RPN13_C~ubiquitin
Common GO terms	GO:0002020 - protease binding GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 407
+	Hs
		924012 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		ADRM1_HUMAN (1-407): 8.77e-165: 470: 100.00
+	Rn
		1144292 UBC_RAT (1-108): 1.27e-29: 127: 90.74		ADRM1_RAT (1-407): 5.91e-166: 473: 96.56
+	Mm
		477031 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		ADRM1_MOUSE (1-407): 8.63e-161: 459: 96.56
+	Hs
		397991 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		ADRM1_HUMAN (1-407): 8.77e-165: 470: 100.00
+	Hs
		475039 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		ADRM1_HUMAN (1-407): 8.77e-165: 470: 100.00