HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	24526689
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Histone~ubiquitin
Common GO terms	GO:0005615 - extracellular space GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 126
+	Hs
		475584 UBC_HUMAN (1-685): 0: 846: 100.00		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		241427 UBC_HUMAN (1-685): 0: 846: 100.00		H2B1K_HUMAN (1-126): 1.56e-53: 165: 98.41
+	Sc
		355744 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		H2B2_YEAST (3-125): 4.73e-37: 124: 71.55
+	Dm
		355277 R9PY16_DROME (457-685): 5.07e-80: 258: 90.39		H2B_DROME (36-126): 9.49e-47: 148: 95.60
+	Hs
		918277 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		924017 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		924103 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41
+	Hs
		241495 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		H2B1K_HUMAN (1-126): 1.56e-53: 165: 98.41
+	Hs
		924129 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		H2B1L_HUMAN (1-126): 2.49e-52: 162: 97.62
+	Hs
		924107 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		H2B1A_HUMAN (1-126): 3.43e-46: 147: 85.04