HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: DDI2 (Q5TDH0)
Protein DDI1 homolog 2 (EC 3.4.23.-)
Gene: DDI2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.899

Property	Details
Experiments	35358511, 37084817, 28190767, 38803224
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	ubiquitin~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 399
+	Hs
		476101 UBC_HUMAN (1-685): 0: 846: 100.00		DDI1_HUMAN (1-392): 7.44e-148: 426: 70.75
+	Dm
		477540 UBIQP_DROME (1-610): 0: 752: 99.84		Q9VXF9_DROME (5-395): 2.61e-124: 368: 46.38
+	Hs
		476565 UBC_HUMAN (1-685): 0: 846: 100.00		UBQL1_HUMAN (5-241): 5.78e-49: 176: 14.80
+	Hs
		476525 UBC_HUMAN (1-685): 0: 846: 100.00		UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20
+	Hs
		476438 UBC_HUMAN (1-685): 0: 846: 100.00		UBQL4_HUMAN (8-241): 1.8e-44: 164: 14.59
+	Hs
		475525 UBC_HUMAN (1-685): 0: 846: 100.00		RD23A_HUMAN (3-198): 2.36e-28: 116: 15.00
+	Dm
		1375397 Q9W418_DROME (229-685): 0: 557: 99.78		Q9VXF9_DROME (5-395): 2.61e-124: 368: 46.38
+	Hs
		475590 UBC_HUMAN (1-685): 0: 846: 100.00		RS27A_HUMAN (10-77): 3.2e-14: 71.7: 22.06
+	Xl
		1186353 Q7SY79_XENLA (77-685): 0: 744: 99.84		Q9PVN8_XENLA (31-241): 2.49e-40: 152: 14.46
+	Sp
		477571 UBI4P_SCHPO (305-685): 1.76e-151: 445: 95.80		MUD1_SCHPO (134-393): 2e-83: 259: 38.10
+	Dm
		1362837 Q9W418_DROME (229-685): 0: 557: 99.78		Q9VCD5_DROME (5-227): 2.18e-35: 133: 12.88
+	Sc
		477305 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		DDI1_YEAST (3-395): 7.99e-93: 287: 30.92
+	Hs
		1286323 Q96C32_HUMAN (229-533): 1.87e-118: 358: 99.67		UBQL1_HUMAN (5-241): 5.78e-49: 176: 14.80
+	Sc
		477360 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		DSK2_YEAST (19-213): 6.83e-31: 123: 15.49
+	Sc
		477189 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		RAD23_YEAST (5-202): 3.88e-26: 110: 16.00
+	At
		1091781 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		Q8L745_ARATH (10-120): 1.11e-22: 102: 21.62
+	At
		1247032 RUB2_ARATH (457-608): 1.43e-47: 166: 78.29		DSK2A_ARATH (3-241): 2.42e-52: 184: 18.80
+	Hs
		872136 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		RD23A_HUMAN (3-198): 2.36e-28: 116: 15.00
+	Hs
		923944 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		RS27A_HUMAN (10-77): 3.2e-14: 71.7: 22.06
+	Bt
		924446 RS27A_BOVIN (609-684): 7.23e-41: 148: 100.00		RS27A_BOVIN (10-77): 3.2e-14: 71.7: 22.06