HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: SH3R1 (Q7Z6J0)
E3 ubiquitin-protein ligase SH3RF1 (EC 2.3.2.27) (Plenty of SH3s) (Protein POSH) (RING finger protein 142) (RING-type E3 ubiquitin transferase SH3RF1) (SH3 domain-containing RING finger protein 1) (SH3 multiple domains protein 2)
Gene: SH3RF1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	20696164
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH3_1~ubiquitin, SH3_9~ubiquitin, ubiquitin~zf-C3HC4_2
Common GO terms	GO:0005829 - cytosol GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 888
+	Xl
		1155575 Q7SY79_XENLA (77-685): 0: 744: 99.84		SH3R1_XENLA (1-888): 1.53e-108: 355: 64.54
+	Hs
		475943 UBC_HUMAN (1-685): 0: 846: 100.00		OTOG_HUMAN (355-783): 3.08e-49: 192: 17.27
+	Hs
		208981 UBC_HUMAN (1-685): 0: 846: 100.00		NCK2_HUMAN (101-330): 2.72e-37: 146: 17.26
+	Hs
		476138 UBC_HUMAN (1-685): 0: 846: 100.00		STAM1_HUMAN (420-699): 2.16e-25: 113: 12.84
+	Hs
		276993 UBC_HUMAN (1-685): 0: 846: 100.00		STAM2_HUMAN (436-755): 1.43e-22: 104: 13.81
+	Hs
		476483 UBC_HUMAN (1-685): 0: 846: 100.00		ITSN2_HUMAN (117-266): 1.18e-14: 81: 18.99
+	Hs
		475816 UBC_HUMAN (1-685): 0: 846: 100.00		ITSN1_HUMAN (551-888): 1.75e-12: 73.7: 12.83
+	Hs
		476640 UBC_HUMAN (1-685): 0: 846: 100.00		CD2AP_HUMAN (764-888): 1.62e-12: 73.3: 30.47
+	Hs
		475936 UBC_HUMAN (1-685): 0: 846: 100.00		DNMBP_HUMAN (4-190): 5.38e-11: 68.9: 15.10
+	Hs
		476095 UBC_HUMAN (1-685): 0: 846: 100.00		SH3R3_HUMAN (691-888): 1.88e-10: 66.8: 20.71
+	Hs
		924099 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		STAM1_HUMAN (420-699): 2.16e-25: 113: 12.84
+	Hs
		277047 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		STAM2_HUMAN (436-755): 1.43e-22: 104: 13.81
+	Mm
		476756 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		STAM1_MOUSE (420-755): 9.59e-26: 114: 15.19
+	Hs
		596208 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		NEBU_HUMAN (27-189): 1.24e-17: 91.1: 17.58
+	Rn
		78185 UBC_RAT (1-108): 1.27e-29: 127: 90.74		B5DF55_RAT (420-699): 1.15e-24: 111: 12.42
+	Mm
		292343 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		STAM2_MOUSE (436-731): 6.03e-19: 93.4: 12.05
+	Hs
		276992 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		STAM2_HUMAN (436-755): 1.43e-22: 104: 13.81
+	Mm
		70590 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		B2RR82_MOUSE (124-218): 1.74e-15: 83.7: 25.26
+	Rn
		193639 UBC_RAT (1-108): 1.27e-29: 127: 90.74		SH3G1_RAT (234-509): 5.55e-16: 82.6: 13.41
+	Mm
		477062 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		ITSN1_MOUSE (184-888): 5.2e-09: 62.6: 12.10