HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: UEVLD (Q8IX04)
Ubiquitin-conjugating enzyme E2 variant 3 (UEV-3) (EV and lactate/malate dehydrogenase domain-containing protein)
Gene: UEVLD

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	23314748
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UEV~ubiquitin
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 471
+	Hs
		334112 UBC_HUMAN (1-685): 0: 846: 100.00		LDHA_HUMAN (164-471): 1.18e-135: 395: 37.65
+	Hs
		421950 UBC_HUMAN (1-685): 0: 846: 100.00		LDHB_HUMAN (164-470): 4.76e-128: 376: 37.05
+	Hs
		476268 UBC_HUMAN (1-685): 0: 846: 100.00		TS101_HUMAN (8-144): 1.48e-74: 241: 55.47
+	Hs
		398028 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		UEVLD_HUMAN (1-471): 0: 553: 100.00
+	At
		1092443 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		MDHM1_ARATH (156-471): 1.81e-114: 341: 17.46
+	At
		1092136 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		MDHM2_ARATH (156-471): 4.4e-113: 338: 17.75
+	At
		1092365 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		MDHP_ARATH (180-469): 1.1e-100: 308: 19.11
+	Rn
		387841 UBC_RAT (1-108): 1.27e-29: 127: 90.74		LDHA_RAT (164-471): 1.23e-133: 390: 38.55
+	Hs
		334102 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		LDHA_HUMAN (164-471): 1.18e-135: 395: 37.65
+	Rn
		785619 UBC_RAT (1-108): 1.27e-29: 127: 90.74		LDHB_RAT (164-470): 9.91e-127: 373: 37.05
+	Hs
		397723 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		LDHB_HUMAN (164-470): 4.76e-128: 376: 37.05
+	Mm
		476825 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		TS101_MOUSE (8-146): 3.86e-73: 237: 53.24
+	Hs
		475159 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		TS101_HUMAN (8-144): 1.48e-74: 241: 55.47