HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: KLHL7 (Q8IXQ5)
Kelch-like protein 7
Gene: KLHL7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.602

Property	Details
Experiments	28190767, 21828050
Identification Methods	pull down, enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016567 - protein ubiquitination
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 586
+	Hs
		475860 UBC_HUMAN (1-685): 0: 846: 100.00		KLH12_HUMAN (26-573): 9.01e-166: 485: 31.12
+	Hs
		476473 UBC_HUMAN (1-685): 0: 846: 100.00		KLH28_HUMAN (26-573): 3.5e-156: 461: 29.59
+	Hs
		476498 UBC_HUMAN (1-685): 0: 846: 100.00		KLH13_HUMAN (383-578): 5.12e-46: 173: 23.23
+	Hs
		475742 UBC_HUMAN (1-685): 0: 846: 100.00		KEAP1_HUMAN (417-586): 7.63e-33: 135: 20.12
+	Mm
		476979 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		KLH28_MOUSE (26-573): 3.92e-155: 458: 29.41
+	Mm
		477071 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		KEAP1_MOUSE (428-586): 1.22e-31: 131: 19.02
+	Rn
		1144236 UBC_RAT (1-108): 1.27e-29: 127: 90.74		KLH17_RAT (279-429): 1.18e-21: 101: 23.08
+	Mm
		476912 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		KLHL2_MOUSE (482-586): 2.52e-18: 90.6: 20.95
+	Hs
		397998 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		KLH26_HUMAN (432-586): 5.29e-20: 96: 15.53