HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: PDC6I (Q8WUM4)
Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (ALG-2-interacting protein X) (Hp95)
Gene: PDCD6IP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	28190767, 33141564, 37010382, 38803224
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 868
+	Hs
		476367 UBC_HUMAN (1-685): 0: 846: 100.00		PTN23_HUMAN (3-868): 1.49e-131: 432: 23.93
+	Hs
		475644 UBC_HUMAN (1-685): 0: 846: 100.00		CENPE_HUMAN (218-699): 3.42e-67: 247: 14.20
+	Hs
		475417 UBC_HUMAN (1-685): 0: 846: 100.00		MYH9_HUMAN (163-716): 5.84e-59: 221: 15.01
+	Hs
		475291 UBC_HUMAN (1-685): 0: 846: 100.00		MYH1_HUMAN (137-717): 1.19e-53: 205: 11.24
+	Hs
		475874 UBC_HUMAN (1-685): 0: 846: 100.00		TGO1_HUMAN (241-868): 3.47e-45: 178: 11.69
+	Hs
		475671 UBC_HUMAN (1-685): 0: 846: 100.00		EP300_HUMAN (527-867): 6.39e-32: 136: 13.70
+	Hs
		60548 UBC_HUMAN (1-685): 0: 846: 100.00		VP37C_HUMAN (540-856): 2.14e-25: 110: 18.81
+	Rn
		1144297 UBC_RAT (1-108): 1.27e-29: 127: 90.74		PDC6I_RAT (1-868): 0: 650: 91.64
+	Sc
		477482 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		PALA_YEAST (1-714): 1.72e-115: 368: 24.48
+	Sc
		477361 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		BRO1_YEAST (1-804): 8.13e-106: 348: 21.37
+	At
		95243 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		BRO1_ARATH (4-829): 3.98e-139: 436: 25.06
+	Hs
		924163 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		PTN23_HUMAN (3-868): 1.49e-131: 432: 23.93
+	Mm
		476930 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		MYH9_MOUSE (163-716): 3.19e-60: 225: 15.48
+	Hs
		397813 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		MYH9_HUMAN (163-716): 5.84e-59: 221: 15.01
+	Mm
		476828 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		MYH10_MOUSE (197-713): 3.92e-42: 169: 13.08
+	Hs
		397814 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		MYH10_HUMAN (197-713): 1.83e-42: 170: 13.08
+	Hs
		397937 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		EP300_HUMAN (527-867): 6.39e-32: 136: 13.70