HitPredict

Interactor 1: A0AQH0 (A0AQH0)
Proteasome subunit beta
Gene: Prosbeta1

Interactor 2: PSMD1 (Q9V3P6)
26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory complex subunit p110) (26S proteasome regulatory subunit RPN2)
Gene: Rpn2

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 224 Dm			1 1020
+	Dm
		1278636 PSA5_DROME (4-212): 3.42e-73: 223: 17.20		PSMD1_DROME (1-1004): 0: 1198: 100.00
+	Hs
		656133 PSB9_HUMAN (7-213): 1.88e-78: 236: 50.73		PSMD1_HUMAN (3-1001): 0: 1176: 60.30
+	Hs
		156342 PSA7_HUMAN (4-214): 2.99e-73: 224: 15.60		PSMD1_HUMAN (3-1001): 0: 1176: 60.30
+	Hs
		656297 PSA5_HUMAN (4-211): 4.41e-73: 223: 15.60		PSMD1_HUMAN (3-1001): 0: 1176: 60.30
+	Hs
		656760 PSB5_HUMAN (11-219): 1.19e-72: 223: 27.14		PSMD1_HUMAN (3-1001): 0: 1176: 60.30
+	Hs
		689 PSA5_HUMAN (4-211): 4.41e-73: 223: 15.60		A0A087WW66_HUMAN (3-1001): 0: 1100: 57.50
+	Hs
		691 PSB5_HUMAN (11-219): 1.19e-72: 223: 27.14		A0A087WW66_HUMAN (3-1001): 0: 1100: 57.50
+	Sc
		625919 PSB2_YEAST (9-211): 3.28e-80: 242: 31.22		RPN2_YEAST (1-1016): 0: 950: 35.74
+	Sc
		693292 PSB1_YEAST (1-208): 1.03e-79: 239: 53.11		RPN2_YEAST (1-1016): 0: 950: 35.74
+	Sc
		675399 PSB5_YEAST (12-201): 1.51e-73: 226: 27.23		RPN2_YEAST (1-1016): 0: 950: 35.74
+	Hs
		656112 PSB9_HUMAN (7-213): 1.88e-78: 236: 50.73		PSMD2_HUMAN (9-812): 0: 757: 16.90
+	Hs
		156281 PSA7_HUMAN (4-214): 2.99e-73: 224: 15.60		PSMD2_HUMAN (9-812): 0: 757: 16.90
+	Hs
		656214 PSA5_HUMAN (4-211): 4.41e-73: 223: 15.60		PSMD2_HUMAN (9-812): 0: 757: 16.90
+	Hs
		656707 PSB5_HUMAN (11-219): 1.19e-72: 223: 27.14		PSMD2_HUMAN (9-812): 0: 757: 16.90
+	Dm
		47629 A0AQH0_DROME (1-224): 1.45e-77: 234: 100.00		Q9VW54_DROME (13-812): 0: 617: 17.03
+	Sp
		675390 PSB5_SCHPO (12-199): 2.13e-82: 248: 26.98		RPN1_SCHPO (9-810): 0: 574: 16.86
+	Sp
		953217 PSA5_SCHPO (4-211): 1.9e-74: 227: 18.72		RPN1_SCHPO (9-810): 0: 574: 16.86
+	Sc
		625931 PSB2_YEAST (9-211): 3.28e-80: 242: 31.22		RPN1_YEAST (9-619): 8.39e-106: 355: 14.66
+	Sc
		751159 PSB1_YEAST (1-208): 1.03e-79: 239: 53.11		RPN1_YEAST (9-619): 8.39e-106: 355: 14.66
+	Sc
		675415 PSB5_YEAST (12-201): 1.51e-73: 226: 27.23		RPN1_YEAST (9-619): 8.39e-106: 355: 14.66