HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	30737378, 38803224
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 488
+	Hs
		475722 UBC_HUMAN (1-685): 0: 846: 100.00		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1038438 Q59EM9_HUMAN (152-685): 0: 661: 99.63		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		476505 UBC_HUMAN (1-685): 0: 846: 100.00		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04
+	Hs
		476103 UBC_HUMAN (1-685): 0: 846: 100.00		HDAC7_HUMAN (29-280): 1.96e-23: 106: 26.37
+	At
		186878 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		HDA19_ARATH (1-482): 0: 592: 55.31
+	At
		1092057 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		HDA6_ARATH (1-467): 0: 578: 57.02
+	Hs
		923981 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Sc
		477487 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		HOS1_YEAST (81-317): 4.82e-47: 171: 36.93
+	Hs
		924205 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04
+	Mm
		477070 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		HDAC6_MOUSE (11-367): 2.93e-104: 338: 24.12
+	Hs
		398126 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04
+	Hs
		171507 UBD_HUMAN (155-304): 5.41e-28: 112: 32.05		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04
+	Hs
		475219 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04