HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: CSN5 (Q92905)
COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1)
Gene: COPS5

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	21145461, 19214193
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	JAB~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 334
+	Hs
		130705 UBC_HUMAN (1-685): 0: 846: 100.00		PSDE_HUMAN (50-331): 1.67e-79: 246: 31.51
+	Hs
		176926 UBC_HUMAN (1-685): 0: 846: 100.00		EIF3H_HUMAN (52-320): 2.17e-66: 214: 18.57
+	Hs
		475500 UBC_HUMAN (1-685): 0: 846: 100.00		PSMD7_HUMAN (52-325): 1.07e-66: 214: 14.79
+	Hs
		124740 UBC_HUMAN (1-685): 0: 846: 100.00		EIF3F_HUMAN (44-328): 3.25e-64: 208: 14.48
+	Hs
		475467 UBC_HUMAN (1-685): 0: 846: 100.00		BRCC3_HUMAN (56-203): 4.61e-43: 152: 21.23
+	Hs
		475895 UBC_HUMAN (1-685): 0: 846: 100.00		MYSM1_HUMAN (39-172): 3.5e-29: 119: 23.29
+	At
		1091793 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		CSN5A_ARATH (1-334): 5.43e-121: 354: 65.69
+	Sc
		477336 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		RPN11_YEAST (39-333): 9.57e-75: 234: 29.14
+	Sc
		477501 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		CSN5_YEAST (22-299): 9.32e-57: 191: 29.51
+	Sc
		477476 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		RPN8_YEAST (53-326): 4.45e-57: 190: 16.61
+	Sp
		477575 UBI4P_SCHPO (305-685): 1.76e-151: 445: 95.80		SST2_SCHPO (74-191): 8.94e-24: 103: 22.95
+	At
		1092172 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		PSDE_ARATH (41-331): 1.05e-80: 249: 31.56
+	Mm
		193512 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		CSN5_MOUSE (1-334): 1.02e-130: 378: 99.40
+	At
		1091969 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		PSD7B_ARATH (46-326): 2.01e-68: 218: 15.17
+	At
		188941 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		PSD7A_ARATH (46-326): 8.54e-69: 218: 14.48
+	At
		1091965 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		EIF3H_ARATH (39-314): 3.35e-59: 195: 17.90
+	Hs
		130837 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		PSDE_HUMAN (50-331): 1.67e-79: 246: 31.51
+	Mm
		192886 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		PSDE_MOUSE (50-331): 1.67e-79: 246: 31.51
+	Mm
		476691 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		PSMD7_MOUSE (52-325): 7.97e-67: 214: 14.79
+	Mm
		476703 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		BRCC3_MOUSE (56-264): 1.19e-44: 156: 18.41