HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: UBP13 (Q92995)
Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.4.19.12) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13)
Gene: USP13

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	1.00	0.969

Property	Details
Experiments	22216260, 28190767, 29576527, 30659753, 31699778, 34642328, 36114200, 38803224, 23314748
Identification Methods	enzymatic study, pull down, unspecified method
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UBA~ubiquitin, UCH~ubiquitin, ubiquitin~zf-UBP
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 863
+	Hs
		475461 UBC_HUMAN (1-685): 0: 846: 100.00		UBP5_HUMAN (26-863): 0: 740: 59.93
+	Hs
		476580 UBC_HUMAN (1-685): 0: 846: 100.00		UBP24_HUMAN (295-815): 1.35e-78: 281: 13.40
+	Hs
		476529 UBC_HUMAN (1-685): 0: 846: 100.00		UBP25_HUMAN (336-854): 7.03e-72: 258: 17.79
+	Hs
		476146 UBC_HUMAN (1-685): 0: 846: 100.00		USP9X_HUMAN (296-701): 3.34e-69: 252: 16.86
+	Hs
		476658 UBC_HUMAN (1-685): 0: 846: 100.00		UBP3_HUMAN (690-858): 2.74e-25: 113: 14.44
+	Hs
		476545 UBC_HUMAN (1-685): 0: 846: 100.00		UBP21_HUMAN (718-859): 5.38e-25: 112: 18.62
+	Hs
		271022 UBC_HUMAN (1-685): 0: 846: 100.00		UBP2_HUMAN (713-859): 1.18e-23: 108: 17.11
+	Hs
		301354 UBC_HUMAN (1-685): 0: 846: 100.00		UBP19_HUMAN (719-863): 1.24e-22: 106: 16.25
+	Hs
		475995 UBC_HUMAN (1-685): 0: 846: 100.00		UBP48_HUMAN (335-614): 2.78e-21: 102: 18.66
+	Hs
		475440 UBC_HUMAN (1-685): 0: 846: 100.00		UBP8_HUMAN (686-861): 1.79e-20: 99.7: 12.64
+	Hs
		475932 UBC_HUMAN (1-685): 0: 846: 100.00		U17L2_HUMAN (663-862): 3.63e-20: 97: 14.15
+	Hs
		476579 UBC_HUMAN (1-685): 0: 846: 100.00		UBP22_HUMAN (712-860): 9.24e-14: 76.9: 12.50
+	Hs
		64200 UBC_HUMAN (1-685): 0: 846: 100.00		UBP27_HUMAN (706-860): 3.58e-13: 74.6: 12.07
+	Hs
		475693 UBC_HUMAN (1-685): 0: 846: 100.00		UBP4_HUMAN (460-606): 2.3e-11: 69.8: 16.34
+	Hs
		800571 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		UBP5_HUMAN (26-863): 0: 740: 59.93
+	At
		1091780 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBP14_ARATH (26-861): 0: 610: 41.86
+	Dm
		477538 UBIQP_DROME (1-610): 0: 752: 99.84		NOT_DROME (723-860): 1.13e-14: 79.6: 14.58
+	Sc
		477245 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		UBP14_YEAST (30-861): 1.93e-134: 421: 23.15
+	Sc
		477294 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		UBP5_YEAST (337-633): 2.72e-26: 117: 15.48
+	Sc
		477366 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		UBP8_YEAST (717-859): 2.7e-14: 78.5: 15.29