HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: USP9X (Q93008)
Ubiquitin carboxyl-terminal hydrolase 9X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets in mammals) (hFAM) (Fat facets protein-related, X-linked) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X)
Gene: USP9X

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	1.00	0.935

Property	Details
Experiments	29576527, 33141564, 34642328, 36114200, 30914461, 23287719
Identification Methods	pull down, affinity chromatography technology, enzymatic study, unspecified method
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UCH~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 2554
+	Hs
		131635 UBC_HUMAN (1-685): 0: 846: 100.00		USP9Y_HUMAN (1-2554): 0: 3611: 91.59
+	Hs
		924100 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		USP9X_HUMAN (1-2554): 0: 3676: 100.00
+	Hs
		476580 UBC_HUMAN (1-685): 0: 846: 100.00		UBP24_HUMAN (36-2478): 0: 2211: 29.78
+	Mm
		69894 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		UBP24_MOUSE (36-2478): 0: 2235: 29.70
+	Hs
		476213 UBC_HUMAN (1-685): 0: 846: 100.00		UBP47_HUMAN (1465-2053): 7.75e-108: 381: 19.49
+	Hs
		475995 UBC_HUMAN (1-685): 0: 846: 100.00		UBP48_HUMAN (1473-2056): 6.89e-105: 365: 20.75
+	Hs
		476147 UBC_HUMAN (1-685): 0: 846: 100.00		UBP7_HUMAN (1469-2119): 8.05e-96: 339: 18.82
+	Hs
		476579 UBC_HUMAN (1-685): 0: 846: 100.00		UBP22_HUMAN (1505-1931): 1.76e-100: 336: 17.68
+	Hs
		64200 UBC_HUMAN (1-685): 0: 846: 100.00		UBP27_HUMAN (1524-1949): 2.29e-96: 321: 17.61
+	Hs
		475932 UBC_HUMAN (1-685): 0: 846: 100.00		U17L2_HUMAN (1517-2009): 1.71e-93: 316: 20.52
+	Hs
		259261 UBC_HUMAN (1-685): 0: 846: 100.00		UBP12_HUMAN (1519-1957): 8.45e-94: 311: 21.51
+	Hs
		475566 UBC_HUMAN (1-685): 0: 846: 100.00		UBP46_HUMAN (1556-1957): 1.38e-89: 299: 21.03
+	Hs
		475952 UBC_HUMAN (1-685): 0: 846: 100.00		UBP34_HUMAN (221-474): 1.84e-77: 290: 25.19
+	Hs
		476452 UBC_HUMAN (1-685): 0: 846: 100.00		UBP40_HUMAN (1545-1884): 1.05e-23: 112: 25.73
+	Sc
		477365 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		UBP15_YEAST (1489-2088): 1.04e-96: 344: 20.59
+	At
		1092066 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBP12_ARATH (1484-2140): 2.97e-124: 425: 18.51
+	At
		1091741 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBP13_ARATH (1486-2161): 4.32e-115: 397: 18.38
+	Mm
		476669 UBB_MOUSE (457-685): 2.3e-86: 275: 99.56		UBP48_MOUSE (1473-2106): 9.99e-103: 359: 19.73
+	Dm
		1099208 R9PY16_DROME (457-685): 5.07e-80: 258: 90.39		UBPE_DROME (1495-2045): 2.26e-99: 357: 20.76
+	Sc
		477366 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		UBP8_YEAST (1555-1921): 2.04e-20: 99.4: 25.13