Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: OTUL (Q96BN8)
Ubiquitin thioesterase otulin (EC 3.4.19.12) (Deubiquitinating enzyme otulin) (OTU domain-containing deubiquitinase with linear linkage specificity) (Ubiquitin thioesterase Gumby)
Gene: OTULIN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.981

The method score is based on:

Property Details
Experiments 29576527, 34315543, 35170849, 25527291, 28319114, 28919039, 31056421, 31541095, 36720498, 23746843, 23708998, 24726327, 23827681
Identification Methods pull down, affinity chromatography technology, enzymatic study, x-ray crystallography
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Peptidase_C101~ubiquitin
Common GO terms GO:0005829 - cytosol
GO:0016567 - protein ubiquitination
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 685
Hs

1 352
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024