HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: BIRC7 (Q96CA5)
Baculoviral IAP repeat-containing protein 7 (EC 2.3.2.27) (Kidney inhibitor of apoptosis protein) (KIAP) (Livin) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (RING finger protein 50) (RING-type E3 ubiquitin transferase BIRC7) [Cleaved into: Baculoviral IAP repeat-containing protein 7 30kDa subunit (Truncated livin) (p30-Livin) (tLivin)]
Gene: BIRC7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	22902369
Identification Methods	x-ray crystallography
Interaction Type	association

Property	Details
Interacting Pfam domains	ubiquitin~zf-C3HC4_3
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016567 - protein ubiquitination
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 298
+	Hs
		476431 UBC_HUMAN (1-685): 0: 846: 100.00		BIRC6_HUMAN (54-252): 6.52e-36: 138: 21.10
+	Hs
		476162 UBC_HUMAN (1-685): 0: 846: 100.00		MIB2_HUMAN (236-297): 7.71e-23: 100: 38.71
+	Hs
		475718 UBC_HUMAN (1-685): 0: 846: 100.00		BIRC3_HUMAN (240-298): 5.43e-20: 92: 71.67
+	Hs
		476011 UBC_HUMAN (1-685): 0: 846: 100.00		MIB1_HUMAN (206-296): 7.37e-20: 91.6: 25.28
+	Hs
		475719 UBC_HUMAN (1-685): 0: 846: 100.00		BIRC2_HUMAN (84-281): 4.95e-19: 88.9: 23.23
+	Hs
		475629 UBC_HUMAN (1-685): 0: 846: 100.00		XIAP_HUMAN (1-96): 3.35e-13: 71.5: 19.19
+	Xl
		1151527 Q7SY79_XENLA (77-685): 0: 744: 99.84		MIB1_XENLA (206-296): 8.26e-20: 91.6: 27.47
+	Dr
		47652 Q6IS68_DANRE (146-685): 0: 661: 98.70		A0AR23_DANRE (237-297): 1.37e-21: 96.8: 36.07
+	Dr
		47643 F1QHN6_DANRE (229-685): 0: 555: 99.78		A0AR23_DANRE (237-297): 1.37e-21: 96.8: 36.07
+	Dr
		47653 Q7SXA3_DANRE (609-684): 4.99e-41: 148: 100.00		A0AR23_DANRE (237-297): 1.37e-21: 96.8: 36.07
+	Mm
		476925 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		MIB2_MOUSE (212-297): 1.16e-22: 99: 30.23
+	Hs
		171467 UBD_HUMAN (155-304): 5.41e-28: 112: 32.05		BIRC5_HUMAN (78-162): 8.85e-30: 111: 32.22
+	Mm
		140018 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		BIRC3_MOUSE (84-161): 1.59e-20: 93.5: 38.46
+	Hs
		475022 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		BIRC3_HUMAN (240-298): 5.43e-20: 92: 71.67
+	Mm
		476824 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		XIAP_MOUSE (1-96): 2.2e-12: 68.9: 18.18
+	Rn
		1144301 UBC_RAT (1-108): 1.27e-29: 127: 90.74		XIAP_RAT (1-96): 1.08e-11: 66.9: 16.16
+	Hs
		474994 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		XIAP_HUMAN (1-96): 3.35e-13: 71.5: 19.19