HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: BIRC6 (Q9NR09)
Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON)
Gene: BIRC6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	1.00	0.834

Property	Details
Experiments	27182664, 38803224, 16196087
Identification Methods	proximity labelling technology, pull down, affinity chromatography technology
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	UQ_con~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 4857
+	Hs
		476332 UBC_HUMAN (1-685): 0: 846: 100.00		UBE2O_HUMAN (4462-4835): 4.24e-76: 283: 25.46
+	Hs
		476388 UBC_HUMAN (1-685): 0: 846: 100.00		UBE2Z_HUMAN (4566-4830): 1.27e-63: 224: 30.97
+	Hs
		475586 UBC_HUMAN (1-685): 0: 846: 100.00		UB2D2_HUMAN (4573-4740): 1.43e-61: 210: 26.79
+	Hs
		475501 UBC_HUMAN (1-685): 0: 846: 100.00		UB2D1_HUMAN (4573-4740): 1.22e-60: 207: 26.79
+	Hs
		476604 UBC_HUMAN (1-685): 0: 846: 100.00		UB2D4_HUMAN (4573-4740): 1.37e-60: 207: 27.38
+	Hs
		475550 UBC_HUMAN (1-685): 0: 846: 100.00		UB2D3_HUMAN (4573-4740): 5.05e-60: 205: 26.79
+	Hs
		475485 UBC_HUMAN (1-685): 0: 846: 100.00		UBE2A_HUMAN (4571-4748): 1.87e-54: 190: 28.09
+	Hs
		475597 UBC_HUMAN (1-685): 0: 846: 100.00		UBE2B_HUMAN (4571-4748): 1.01e-53: 188: 29.21
+	Xl
		919927 Q7SY79_XENLA (77-685): 0: 744: 99.84		UB2D2_XENLA (4573-4740): 1.43e-61: 210: 26.79
+	Hs
		475718 UBC_HUMAN (1-685): 0: 846: 100.00		BIRC3_HUMAN (273-395): 1.46e-20: 101: 21.95
+	Hs
		475629 UBC_HUMAN (1-685): 0: 846: 100.00		XIAP_HUMAN (282-437): 1.32e-20: 100: 14.48
+	Hs
		475719 UBC_HUMAN (1-685): 0: 846: 100.00		BIRC2_HUMAN (254-436): 3.68e-19: 97.5: 12.45
+	Dm
		639414 Q9W418_DROME (229-685): 0: 557: 99.78		UBCD1_DROME (4573-4740): 4.27e-61: 208: 27.38
+	At
		715116 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBC8_ARATH (4573-4740): 2.66e-59: 203: 28.57
+	At
		715157 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBC11_ARATH (4573-4740): 2.99e-59: 203: 27.98
+	At
		715132 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBC9_ARATH (4573-4740): 1.37e-58: 201: 28.57
+	At
		715147 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBC10_ARATH (4573-4740): 1.34e-58: 201: 28.57
+	At
		639385 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBC1_ARATH (4571-4732): 1.12e-51: 182: 29.01
+	Sc
		477415 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		UBC7_YEAST (4603-4704): 1.99e-13: 73.2: 39.82
+	Sc
		477103 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		UBC4_YEAST (4573-4704): 1.46e-11: 67.4: 32.58