HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: UBQL4 (Q9NRR5)
Ubiquilin-4 (Ataxin-1 interacting ubiquitin-like protein) (A1Up) (Ataxin-1 ubiquitin-like-interacting protein A1U) (Connexin43-interacting protein of 75 kDa) (CIP75)
Gene: UBQLN4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	1.00	0.888

Property	Details
Experiments	20940304, 29666234, 31699778, 38803224
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UBA~ubiquitin, ubiquitin~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 601
+	Hs
		476565 UBC_HUMAN (1-685): 0: 846: 100.00		UBQL1_HUMAN (11-601): 1.16e-127: 389: 59.16
+	Hs
		476525 UBC_HUMAN (1-685): 0: 846: 100.00		UBQL2_HUMAN (9-601): 6.99e-118: 365: 51.59
+	Xl
		1186353 Q7SY79_XENLA (77-685): 0: 744: 99.84		Q9PVN8_XENLA (2-601): 1.1e-125: 383: 70.00
+	Hs
		475525 UBC_HUMAN (1-685): 0: 846: 100.00		RD23A_HUMAN (13-318): 1.95e-47: 172: 16.37
+	Hs
		475780 UBC_HUMAN (1-685): 0: 846: 100.00		HERP1_HUMAN (8-384): 1.21e-42: 159: 15.33
+	Hs
		475526 UBC_HUMAN (1-685): 0: 846: 100.00		RD23B_HUMAN (13-275): 2e-37: 145: 18.29
+	Hs
		475591 UBC_HUMAN (1-685): 0: 846: 100.00		RL40_HUMAN (13-103): 6.24e-34: 127: 28.26
+	Hs
		475590 UBC_HUMAN (1-685): 0: 846: 100.00		RS27A_HUMAN (13-99): 1.11e-12: 68.1: 29.55
+	Hs
		1286323 Q96C32_HUMAN (229-533): 1.87e-118: 358: 99.67		UBQL1_HUMAN (11-601): 1.16e-127: 389: 59.16
+	Dm
		574862 Q9W418_DROME (229-685): 0: 557: 99.78		RL40_DROME (13-104): 2.35e-29: 114: 27.96
+	Sc
		477189 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		RAD23_YEAST (12-314): 8.29e-49: 176: 17.70
+	Sc
		477360 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		DSK2_YEAST (12-253): 2.33e-23: 104: 28.63
+	At
		1091732 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		RD23D_ARATH (13-307): 5.4e-47: 171: 13.97
+	At
		1247032 RUB2_ARATH (457-608): 1.43e-47: 166: 78.29		DSK2A_ARATH (19-598): 2.08e-82: 270: 28.76
+	At
		1091733 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		RD23C_ARATH (13-321): 2.25e-41: 156: 13.24
+	At
		1091781 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		Q8L745_ARATH (12-272): 9.25e-39: 154: 17.17
+	Hs
		872136 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		RD23A_HUMAN (13-318): 1.95e-47: 172: 16.37
+	Hs
		923945 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		RL40_HUMAN (13-103): 6.24e-34: 127: 28.26
+	Hs
		923944 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		RS27A_HUMAN (13-99): 1.11e-12: 68.1: 29.55
+	Bt
		924446 RS27A_BOVIN (609-684): 7.23e-41: 148: 100.00		RS27A_BOVIN (13-99): 1.11e-12: 68.1: 29.55