HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: RAD18 (Q9NS91)
E3 ubiquitin-protein ligase RAD18 (EC 2.3.2.27) (Postreplication repair protein RAD18) (hHR18) (hRAD18) (RING finger protein 73) (RING-type E3 ubiquitin transferase RAD18)
Gene: RAD18

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	1.00	0.971

Property	Details
Experiments	20935496, 16196087, 19285159, 25162118, 22742833, 22343915, 25756347, 17550899
Identification Methods	pull down, affinity chromatography technology, x-ray crystallography, protein array
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	ubiquitin~zf-C3HC4_2
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 495
+	Mm
		477039 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RAD18_MOUSE (1-495): 0: 685: 65.36
+	Hs
		475205 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		RAD18_HUMAN (1-495): 0: 695: 100.00
+	Sc
		477085 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		RAD18_YEAST (19-304): 1.7e-96: 301: 25.53