HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: RN216 (Q9NWF9)
E3 ubiquitin-protein ligase RNF216 (EC 2.3.2.27) (RING finger protein 216) (RING-type E3 ubiquitin transferase RNF216) (Triad domain-containing protein 3) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B)
Gene: RNF216

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.602

Property	Details
Experiments	31087003, 38803224
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 866
+	Mm
		476729 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RN216_MOUSE (1-866): 0: 1099: 87.07
+	Hs
		476630 UBC_HUMAN (1-685): 0: 846: 100.00		ARI1_HUMAN (426-784): 2.86e-110: 351: 13.94
+	Hs
		312458 UBC_HUMAN (1-685): 0: 846: 100.00		ARI2_HUMAN (404-784): 5.05e-95: 309: 16.45
+	Hs
		476496 UBC_HUMAN (1-685): 0: 846: 100.00		AKIB1_HUMAN (439-775): 4.12e-73: 262: 13.27
+	Hs
		476187 UBC_HUMAN (1-685): 0: 846: 100.00		RNF31_HUMAN (464-792): 1.29e-65: 240: 15.56
+	Hs
		475976 UBC_HUMAN (1-685): 0: 846: 100.00		R144B_HUMAN (509-738): 8e-63: 215: 20.17
+	Hs
		475494 UBC_HUMAN (1-685): 0: 846: 100.00		R144A_HUMAN (512-738): 1.87e-58: 203: 24.47
+	Hs
		475939 UBC_HUMAN (1-685): 0: 846: 100.00		RN19B_HUMAN (502-744): 4.49e-54: 202: 23.19
+	Dm
		477528 UBIQP_DROME (1-610): 0: 752: 99.84		LUBEL_DROME (407-796): 3.7e-71: 258: 14.53
+	Dm
		1214032 Q9W418_DROME (229-685): 0: 557: 99.78		LUBEL_DROME (407-796): 3.7e-71: 258: 14.53
+	Sc
		477225 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		HEL1_YEAST (433-784): 1.25e-82: 277: 14.36
+	At
		1092233 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		Q9M1E9_ARATH (440-754): 2.87e-62: 217: 20.49
+	Hs
		312457 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		ARI2_HUMAN (404-784): 5.05e-95: 309: 16.45
+	Hs
		475094 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		CUL9_HUMAN (436-778): 5.96e-76: 273: 15.86
+	Mm
		476959 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RNF31_MOUSE (464-796): 7.86e-66: 240: 15.64
+	Hs
		475133 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		RNF31_HUMAN (464-792): 1.29e-65: 240: 15.56
+	Hs
		475069 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		RN19B_HUMAN (502-744): 4.49e-54: 202: 23.19