HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: UBP36 (Q9P275)
Ubiquitin carboxyl-terminal hydrolase 36 (EC 2.3.2.-) (EC 3.4.19.12) (Deubiquitinating enzyme 36) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36)
Gene: USP36

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	29576527, 33141564
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UCH~ubiquitin
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 1123
+	Hs
		475932 UBC_HUMAN (1-685): 0: 846: 100.00		U17L2_HUMAN (58-570): 3.3e-118: 377: 37.43
+	Hs
		476579 UBC_HUMAN (1-685): 0: 846: 100.00		UBP22_HUMAN (109-427): 7.21e-113: 362: 25.62
+	Hs
		476400 UBC_HUMAN (1-685): 0: 846: 100.00		UBP42_HUMAN (1-1023): 1.74e-104: 359: 31.00
+	Hs
		64200 UBC_HUMAN (1-685): 0: 846: 100.00		UBP27_HUMAN (109-440): 9.55e-109: 349: 24.53
+	Hs
		475566 UBC_HUMAN (1-685): 0: 846: 100.00		UBP46_HUMAN (101-424): 5.2e-109: 346: 24.37
+	Hs
		259261 UBC_HUMAN (1-685): 0: 846: 100.00		UBP12_HUMAN (102-424): 5.66e-108: 344: 24.16
+	Hs
		475952 UBC_HUMAN (1-685): 0: 846: 100.00		UBP34_HUMAN (8-456): 3.65e-95: 337: 19.51
+	Hs
		476580 UBC_HUMAN (1-685): 0: 846: 100.00		UBP24_HUMAN (11-525): 1.31e-94: 335: 18.24
+	Hs
		271022 UBC_HUMAN (1-685): 0: 846: 100.00		UBP2_HUMAN (8-428): 1.38e-97: 324: 26.14
+	Hs
		476658 UBC_HUMAN (1-685): 0: 846: 100.00		UBP3_HUMAN (75-431): 1.55e-96: 319: 25.61
+	Dm
		477538 UBIQP_DROME (1-610): 0: 752: 99.84		NOT_DROME (18-427): 1.13e-107: 347: 24.22
+	Hs
		475954 UBC_HUMAN (1-685): 0: 846: 100.00		UBP31_HUMAN (120-280): 1e-31: 137: 23.44
+	At
		1210479 UBQ10_ARATH (305-685): 2.63e-153: 453: 95.80		UBP15_ARATH (43-566): 9.99e-111: 369: 26.48
+	Hs
		924201 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		UBP36_HUMAN (1-1123): 0: 646: 100.00
+	Sc
		477294 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		UBP5_YEAST (38-422): 2.9e-103: 345: 23.84
+	Sc
		477366 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		UBP8_YEAST (59-424): 2.3e-100: 327: 25.50
+	Mm
		476669 UBB_MOUSE (457-685): 2.3e-86: 275: 99.56		UBP48_MOUSE (115-935): 4.08e-110: 370: 15.13
+	At
		1092065 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBP15_ARATH (43-566): 9.99e-111: 369: 26.48
+	At
		1092066 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBP12_ARATH (41-618): 2.53e-95: 331: 15.45
+	At
		1091741 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBP13_ARATH (40-619): 2.23e-94: 328: 15.23