HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: UBQL2 (Q9UHD9)
Ubiquilin-2 (Chap1) (DSK2 homolog) (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC-2) (Ubiquitin-like product Chap1/Dsk2)
Gene: UBQLN2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	1.00	0.979

Property	Details
Experiments	32296183, 31699778, 34356632, 36114200, 38803224, 26075709, 27477512, 29526694, 30982635, 28286874, 37824531, unassigned1304
Identification Methods	two hybrid, pull down, x-ray crystallography, affinity chromatography technology, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	UBA~ubiquitin, ubiquitin~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 624
+	Hs
		476565 UBC_HUMAN (1-685): 0: 846: 100.00		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Hs
		476438 UBC_HUMAN (1-685): 0: 846: 100.00		UBQL4_HUMAN (22-624): 2.17e-124: 382: 54.55
+	Xl
		1186353 Q7SY79_XENLA (77-685): 0: 744: 99.84		Q9PVN8_XENLA (14-624): 7.22e-124: 380: 52.43
+	Hs
		476101 UBC_HUMAN (1-685): 0: 846: 100.00		DDI1_HUMAN (43-314): 2.92e-54: 191: 15.60
+	Hs
		475888 UBC_HUMAN (1-685): 0: 846: 100.00		DDI2_HUMAN (43-314): 6.26e-52: 185: 14.59
+	Hs
		475591 UBC_HUMAN (1-685): 0: 846: 100.00		RL40_HUMAN (33-112): 7.49e-34: 127: 30.86
+	Hs
		475590 UBC_HUMAN (1-685): 0: 846: 100.00		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Dm
		477540 UBIQP_DROME (1-610): 0: 752: 99.84		Q9VXF9_DROME (33-313): 1.35e-51: 186: 15.86
+	Hs
		1286323 Q96C32_HUMAN (229-533): 1.87e-118: 358: 99.67		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Dm
		1375397 Q9W418_DROME (229-685): 0: 557: 99.78		Q9VXF9_DROME (33-313): 1.35e-51: 186: 15.86
+	Dm
		1362837 Q9W418_DROME (229-685): 0: 557: 99.78		Q9VCD5_DROME (33-258): 3.37e-32: 127: 15.58
+	Dm
		574862 Q9W418_DROME (229-685): 0: 557: 99.78		RL40_DROME (33-112): 3.08e-31: 120: 30.86
+	Hs
		924208 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		924216 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Sc
		477360 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		DSK2_YEAST (32-239): 1.13e-31: 128: 31.19
+	At
		1247032 RUB2_ARATH (457-608): 1.43e-47: 166: 78.29		DSK2A_ARATH (15-544): 4.66e-86: 280: 27.56
+	Mm
		57049 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		DDI2_MOUSE (43-314): 2.65e-52: 186: 15.11
+	Hs
		923945 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		RL40_HUMAN (33-112): 7.49e-34: 127: 30.86
+	Hs
		923944 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Bt
		924446 RS27A_BOVIN (609-684): 7.23e-41: 148: 100.00		RS27A_BOVIN (33-119): 4.49e-24: 100: 27.27